HCSGD entry for ATP2A3

1. General information

Official gene symbolATP2A3
Entrez ID489
Gene full nameATPase, Ca++ transporting, ubiquitous
Other gene symbolsSERCA3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005388Calcium-transporting ATPase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0006200ATP catabolic processTASbiological_process
GO:0006810TransportTASbiological_process
GO:0006816Calcium ion transportTASbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0008152Metabolic processTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016529Sarcoplasmic reticulumIDAcellular_component
GO:0031095Platelet dense tubular network membraneTAScellular_component
GO:0031965Nuclear membraneIEAcellular_component
GO:0033017Sarcoplasmic reticulum membraneIEAcellular_component
GO:0034220Ion transmembrane transportTASbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0055085Transmembrane transportTASbiological_process
GO:0070588Calcium ion transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.08534834920.85317093580.61386131591.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0555684537
GSE13712_SHEARDown-2.3959534864
GSE13712_STATICDown-0.1710280748
GSE19018Up0.1539394411
GSE19899_A1Up0.0850317596
GSE19899_A2Up0.4672480385
PubMed_21979375_A1Up0.9126253942
PubMed_21979375_A2Up0.4558614817
GSE35957Down-0.0665569452
GSE36640Down-0.0488559710
GSE54402Up0.4741235481
GSE9593Up0.0411798649
GSE43922Up0.6702368254
GSE24585Up0.3109466126
GSE37065Down-0.0053192315
GSE28863_A1Down-0.0388804988
GSE28863_A2Up0.2356005318
GSE28863_A3Up0.2398473584
GSE28863_A4Up0.0466466004
GSE48662Up0.1127632169

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.