HCSGD entry for NUP98


1. General information

Official gene symbolNUP98
Entrez ID4928
Gene full namenucleoporin 98kDa
Other gene symbolsADIR2 NUP196 NUP96
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000059Protein import into nucleus, dockingNASbiological_process
GO:0000278Mitotic cell cycleTASbiological_process
GO:0000776KinetochoreIDAcellular_component
GO:0005215Transporter activityTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005635Nuclear envelopeIDA TAScellular_component
GO:0005643Nuclear poreIDA IEA NAScellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005829CytosolTAScellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0006260DNA replicationIMPbiological_process
GO:0006810TransportIEAbiological_process
GO:0006913Nucleocytoplasmic transportTASbiological_process
GO:0006999Nuclear pore organizationNASbiological_process
GO:0007077Mitotic nuclear envelope disassemblyTASbiological_process
GO:0008645Hexose transportTASbiological_process
GO:0010827Regulation of glucose transportTASbiological_process
GO:0015758Glucose transportTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0017056Structural constituent of nuclear poreIMP NASmolecular_function
GO:0019221Cytokine-mediated signaling pathwayTASbiological_process
GO:0031080Nuclear pore outer ringIDA NAScellular_component
GO:0031965Nuclear membraneIDAcellular_component
GO:0034399Nuclear peripheryIDAcellular_component
GO:0042277Peptide bindingIEAmolecular_function
GO:0042405Nuclear inclusion bodyIDAcellular_component
GO:0044281Small molecule metabolic processTASbiological_process
GO:0044615Nuclear pore nuclear basketIDAcellular_component
GO:0051028MRNA transportIEAbiological_process
GO:0051292Nuclear pore complex assemblyIMPbiological_process
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15881398500.67824444740.79019714561.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0561260684
GSE13712_SHEARUp0.0246607733
GSE13712_STATICUp0.0898830067
GSE19018Down-0.4532256294
GSE19899_A1Down-0.0794725400
GSE19899_A2Up0.2606448805
PubMed_21979375_A1Up0.6726684403
PubMed_21979375_A2Up0.8472650528
GSE35957Down-0.2474898274
GSE36640Down-0.5438140823
GSE54402Up0.4145749084
GSE9593Down-0.1429178174
GSE43922Up0.0604750456
GSE24585Down-0.0529367883
GSE37065Down-0.0402116695
GSE28863_A1Up0.3879095754
GSE28863_A2Up0.4314535431
GSE28863_A3Down-0.1205888385
GSE28863_A4Up0.2429061765
GSE48662Down-0.2108490249

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-34a-5pMIMAT0000255MIRT025511ProteomicsFunctional MTI (Weak)21566225
hsa-miR-98-5pMIMAT0000096MIRT027735MicroarrayFunctional MTI (Weak)19088304
hsa-miR-652-3pMIMAT0003322MIRT039534CLASHFunctional MTI (Weak)23622248
hsa-miR-18a-3pMIMAT0002891MIRT040801CLASHFunctional MTI (Weak)23622248
hsa-miR-149-5pMIMAT0000450MIRT045389CLASHFunctional MTI (Weak)23622248
hsa-miR-30a-3pMIMAT0000088MIRT049913CLASHFunctional MTI (Weak)23622248
hsa-miR-16-5pMIMAT0000069MIRT051267CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.