HCSGD entry for OXA1L
1. General information
| Official gene symbol | OXA1L |
|---|---|
| Entrez ID | 5018 |
| Gene full name | oxidase (cytochrome c) assembly 1-like |
| Other gene symbols | OXA1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0005746 | Mitochondrial respiratory chain | NAS | cellular_component |
| GO:0006461 | Protein complex assembly | NAS | biological_process |
| GO:0009060 | Aerobic respiration | IMP NAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0031966 | Mitochondrial membrane | IDA | cellular_component |
| GO:0032592 | Integral component of mitochondrial membrane | IDA | cellular_component |
| GO:0032780 | Negative regulation of ATPase activity | IMP | biological_process |
| GO:0032981 | Mitochondrial respiratory chain complex I assembly | IMP | biological_process |
| GO:0033615 | Mitochondrial proton-transporting ATP synthase complex assembly | IMP | biological_process |
| GO:0042803 | Protein homodimerization activity | IDA | molecular_function |
| GO:0043234 | Protein complex | IDA | cellular_component |
| GO:0051205 | Protein insertion into membrane | IEA | biological_process |
| GO:0051262 | Protein tetramerization | IDA | biological_process |
| GO:0051354 | Negative regulation of oxidoreductase activity | IMP | biological_process |
| GO:0055114 | Oxidation-reduction process | NAS | biological_process |
| GO:0097031 | Mitochondrial respiratory chain complex I biogenesis | IMP | biological_process |
| GO:0097177 | Mitochondrial ribosome binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0433567988 | 0.9680820789 | 0.4634084044 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.8513173293 |
| GSE13712_SHEAR | Down | -0.2728999684 |
| GSE13712_STATIC | Down | -0.0263909626 |
| GSE19018 | Up | 0.0358520738 |
| GSE19899_A1 | Up | 0.2985435513 |
| GSE19899_A2 | Up | 0.4580822950 |
| PubMed_21979375_A1 | Up | 0.5006323472 |
| PubMed_21979375_A2 | Up | 0.5059089669 |
| GSE35957 | Down | -0.0488122996 |
| GSE36640 | Up | 0.1347238562 |
| GSE54402 | Up | 0.3094841953 |
| GSE9593 | Up | 0.0371851156 |
| GSE43922 | Up | 0.1894469850 |
| GSE24585 | Up | 0.2787681651 |
| GSE37065 | Up | 0.1321641168 |
| GSE28863_A1 | Up | 0.2674361559 |
| GSE28863_A2 | Down | -0.0841257580 |
| GSE28863_A3 | Down | -0.1894985806 |
| GSE28863_A4 | Up | 0.0984733154 |
| GSE48662 | Up | 0.0308968803 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027618 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029718 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032317 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-301b | MIMAT0004958 | MIRT036700 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038752 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-671-5p | MIMAT0003880 | MIRT039277 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048480 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
