HCSGD entry for P2RX5

1. General information

Official gene symbolP2RX5
Entrez ID5026
Gene full namepurinergic receptor P2X, ligand-gated ion channel, 5
Other gene symbolsLRH-1 P2X5 P2X5R
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001614Purinergic nucleotide receptor activityIBA IEA NASmolecular_function
GO:0004888Transmembrane signaling receptor activityTASmolecular_function
GO:0004931Extracellular ATP-gated cation channel activityIBA NASmolecular_function
GO:0005216Ion channel activityIEA TASmolecular_function
GO:0005524ATP bindingIEA NASmolecular_function
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006810TransportTASbiological_process
GO:0006812Cation transportIBAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007399Nervous system developmentTASbiological_process
GO:0010524Positive regulation of calcium ion transport into cytosolNASbiological_process
GO:0016020MembraneIBA IEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0034220Ion transmembrane transportIBA NAS TASbiological_process
GO:0035587Purinergic receptor signaling pathwayIBA NASbiological_process
GO:0035590Purinergic nucleotide receptor signaling pathwayIBA NASbiological_process
GO:0050850Positive regulation of calcium-mediated signalingNASbiological_process
GO:0055085Transmembrane transportIBA NAS TASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00022740020.99640027730.04367183101.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3713560092
GSE13712_SHEARUp1.6307710767
GSE13712_STATICDown-0.0505542880
GSE19018Up0.9674846802
GSE19899_A1Up0.8441692261
GSE19899_A2Up2.3909441620
PubMed_21979375_A1Up3.8495901880
PubMed_21979375_A2Up3.5739973892
GSE35957Down-0.1339407668
GSE36640Up4.1166836800
GSE54402Up0.3578555642
GSE9593Down-0.1921421731
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0080972273

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-98-5pMIMAT0000096MIRT027737MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.