HCSGD entry for GEMIN4
1. General information
| Official gene symbol | GEMIN4 |
|---|---|
| Entrez ID | 50628 |
| Gene full name | gem (nuclear organelle) associated protein 4 |
| Other gene symbols | HC56 HCAP1 HHRF-1 p97 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000387 | Spliceosomal snRNP assembly | IDA TAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005681 | Spliceosomal complex | IEA | cellular_component |
| GO:0005730 | Nucleolus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005829 | Cytosol | IDA TAS | cellular_component |
| GO:0006364 | RRNA processing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0030532 | Small nuclear ribonucleoprotein complex | TAS | cellular_component |
| GO:0032797 | SMN complex | IDA | cellular_component |
| GO:0034660 | NcRNA metabolic process | TAS | biological_process |
| GO:0034719 | SMN-Sm protein complex | IDA | cellular_component |
| GO:0097504 | Gemini of coiled bodies | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0250477603 | 0.4782651077 | 0.3727984172 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0325055633 |
| GSE13712_SHEAR | Up | 0.2208748442 |
| GSE13712_STATIC | Up | 0.2910150323 |
| GSE19018 | Down | -0.0038633077 |
| GSE19899_A1 | Up | 0.3214986973 |
| GSE19899_A2 | Up | 0.7387239231 |
| PubMed_21979375_A1 | Up | 2.2995374391 |
| PubMed_21979375_A2 | Up | 1.2468172780 |
| GSE35957 | Down | -0.4392152422 |
| GSE36640 | Down | -0.8327994041 |
| GSE54402 | Up | 0.4973297880 |
| GSE9593 | Down | -0.7422185012 |
| GSE43922 | Up | 0.5493021937 |
| GSE24585 | Down | -0.5562027186 |
| GSE37065 | Down | -0.0466642589 |
| GSE28863_A1 | Up | 0.6263325863 |
| GSE28863_A2 | Up | 0.0667358088 |
| GSE28863_A3 | Up | 0.0087161814 |
| GSE28863_A4 | Up | 0.0367991624 |
| GSE48662 | Down | -0.3288191482 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-342-3p | MIMAT0000753 | MIRT005881 | Luciferase reporter assay//Northern blot//qRT-PCR | Functional MTI | 21172025 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT032030 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041307 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041966 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043366 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-28-5p | MIMAT0000085 | MIRT049997 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
