HCSGD entry for ATP5C1


1. General information

Official gene symbolATP5C1
Entrez ID509
Gene full nameATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
Other gene symbolsATP5C ATP5CL1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000275Mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)NAScellular_component
GO:0005739MitochondrionISS NAScellular_component
GO:0005743Mitochondrial inner membraneIEA ISScellular_component
GO:0005753Mitochondrial proton-transporting ATP synthase complexIDAcellular_component
GO:0005759Mitochondrial matrixTAScellular_component
GO:0006119Oxidative phosphorylationNASbiological_process
GO:0006200ATP catabolic processIDA NASbiological_process
GO:0006754ATP biosynthetic processNASbiological_process
GO:0015986ATP synthesis coupled proton transportIEAbiological_process
GO:0016887ATPase activityIDA NASmolecular_function
GO:0022857Transmembrane transporter activityICmolecular_function
GO:0022904Respiratory electron transport chainTASbiological_process
GO:0042776Mitochondrial ATP synthesis coupled proton transportIC TASbiological_process
GO:0044237Cellular metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045261Proton-transporting ATP synthase complex, catalytic core F(1)IEAcellular_component
GO:0046933Proton-transporting ATP synthase activity, rotational mechanismIEAmolecular_function
GO:0046961Proton-transporting ATPase activity, rotational mechanismIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.96405615670.12035930630.99999024730.6662412829

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0964097258
GSE13712_SHEARDown-0.0201235564
GSE13712_STATICDown-0.0116866726
GSE19018Up0.0486324074
GSE19899_A1Down-0.0412877679
GSE19899_A2Down-0.4818280528
PubMed_21979375_A1Down-0.3057331664
PubMed_21979375_A2Down-0.1208733056
GSE35957Down-0.4841185934
GSE36640Up0.0400468484
GSE54402Down-0.0915053773
GSE9593Down-0.3598248087
GSE43922Down-0.1539756212
GSE24585Down-0.1181190782
GSE37065Up0.0380918831
GSE28863_A1Down-0.0231571436
GSE28863_A2Up0.1952111529
GSE28863_A3Down-0.5028179495
GSE28863_A4Up0.1107416149
GSE48662Down-0.4751267050

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

QuercetinDB04216 EXPT02732
1-ACETYL-2-CARBOXYPIPERIDINEDB07384 -
AUROVERTIN BDB07394 -
PICEATANNOLDB08399 -
N1-(2-AMINO-4-METHYLPENTYL)OCTAHYDRO-PYRROLO[1,2-A] PYRIMIDINEDB08629 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-30b-5pMIMAT0000420MIRT046113CLASHFunctional MTI (Weak)23622248
hsa-miR-16-5pMIMAT0000069MIRT051299CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.