HCSGD entry for PCBP1
1. General information
| Official gene symbol | PCBP1 |
|---|---|
| Entrez ID | 5093 |
| Gene full name | poly(rC) binding protein 1 |
| Other gene symbols | HNRPE1 HNRPX hnRNP-E1 hnRNP-X |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000398 | MRNA splicing, via spliceosome | TAS | biological_process |
| GO:0003697 | Single-stranded DNA binding | IDA | molecular_function |
| GO:0003723 | RNA binding | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0030529 | Ribonucleoprotein complex | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9458085749 | 0.0548241100 | 0.9999902473 | 0.4416935129 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0460918956 |
| GSE13712_SHEAR | Down | -0.3454287024 |
| GSE13712_STATIC | Down | -0.2485897016 |
| GSE19018 | Down | -0.0084528165 |
| GSE19899_A1 | Down | -0.3554945532 |
| GSE19899_A2 | Up | 0.0106267482 |
| PubMed_21979375_A1 | Down | -0.2523880422 |
| PubMed_21979375_A2 | Up | 0.1188933538 |
| GSE35957 | Down | -0.3051621369 |
| GSE36640 | Down | -0.6699336316 |
| GSE54402 | Up | 0.0541155953 |
| GSE9593 | Down | -0.1897549910 |
| GSE43922 | Down | -0.0687709755 |
| GSE24585 | Down | -0.5449419797 |
| GSE37065 | Down | -0.0776507821 |
| GSE28863_A1 | Up | 0.1153234287 |
| GSE28863_A2 | Up | 0.7603205863 |
| GSE28863_A3 | Down | -0.0172935147 |
| GSE28863_A4 | Down | -0.3673734606 |
| GSE48662 | Down | -0.3075591027 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-21-5p | MIMAT0000076 | MIRT004814 | Quantitative proteomic approach | Functional MTI (Weak) | 19253296 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT004814 | Luciferase reporter assay | Functional MTI | 22316494 |
| hsa-miR-1180-3p | MIMAT0005825 | MIRT035937 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1296-5p | MIMAT0005794 | MIRT036126 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-5p | MIMAT0004748 | MIRT038098 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048509 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
