HCSGD entry for DERL2

1. General information

Official gene symbolDERL2
Entrez ID51009
Gene full namederlin 2
Other gene symbolsF-LAN-1 F-LANa FLANa
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001967Suckling behaviorIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005769Early endosomeIEAcellular_component
GO:0005770Late endosomeIEAcellular_component
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0008284Positive regulation of cell proliferationIDAbiological_process
GO:0030176Integral component of endoplasmic reticulum membraneIDAcellular_component
GO:0030307Positive regulation of cell growthIDAbiological_process
GO:0030433ER-associated ubiquitin-dependent protein catabolic processIMPbiological_process
GO:0030968Endoplasmic reticulum unfolded protein responseIDAbiological_process
GO:0030970Retrograde protein transport, ER to cytosolIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.94931327080.04904101290.99999024730.4139020513

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2735674885
GSE13712_SHEARDown-0.3784192248
GSE13712_STATICDown-0.1005702979
GSE19018Down-0.7064084800
GSE19899_A1Down-0.1410908543
GSE19899_A2Down-0.6448877235
PubMed_21979375_A1Down-0.6408113515
PubMed_21979375_A2Down-0.3432053503
GSE35957Up0.1144570663
GSE36640Up0.2009260506
GSE54402Down-0.1018120148
GSE9593Down-0.0098321246
GSE43922Down-0.0879395407
GSE24585Up0.1824904854
GSE37065Up0.1647829111
GSE28863_A1Down-0.2000758554
GSE28863_A2Down-0.2572698881
GSE28863_A3Down-0.6347446530
GSE28863_A4Up0.1835988566
GSE48662Down-0.2573954649

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-324-3pMIMAT0000762MIRT042933CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.