HCSGD entry for PCM1

1. General information

Official gene symbolPCM1
Entrez ID5108
Gene full namepericentriolar material 1
Other gene symbolsPTC4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000086G2/M transition of mitotic cell cycleTASbiological_process
GO:0000242Pericentriolar materialIEA ISScellular_component
GO:0000278Mitotic cell cycleTASbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIDA ISScellular_component
GO:0005813CentrosomeIDA ISScellular_component
GO:0005829CytosolTAScellular_component
GO:0022027Interkinetic nuclear migrationIEA ISSbiological_process
GO:0031513Nonmotile primary ciliumIDAcellular_component
GO:0031965Nuclear membraneIDAcellular_component
GO:0034451Centriolar satelliteIDA IEAcellular_component
GO:0034453Microtubule anchoringISSbiological_process
GO:0034454Microtubule anchoring at centrosomeIEAbiological_process
GO:0042384Cilium assemblyIMPbiological_process
GO:0042802Identical protein bindingISSmolecular_function
GO:0050768Negative regulation of neurogenesisIEA ISSbiological_process
GO:0051297Centrosome organizationIMPbiological_process
GO:0071539Protein localization to centrosomeIEA ISSbiological_process
GO:0097150Neuronal stem cell maintenanceIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.13471777670.41006940470.74333895971.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0711080393
GSE13712_SHEARDown-0.1373241935
GSE13712_STATICDown-0.1140644378
GSE19018Up0.2632030880
GSE19899_A1Up0.0830394433
GSE19899_A2Down-0.3057383515
PubMed_21979375_A1Down-0.4421528006
PubMed_21979375_A2Up0.0085625370
GSE35957Up0.0148076032
GSE36640Down-0.6591394068
GSE54402Down-0.2423214076
GSE9593Up0.1255512859
GSE43922Down-0.0093402744
GSE24585Up0.2593080631
GSE37065Down-0.0035386846
GSE28863_A1Up1.5589023656
GSE28863_A2Up1.4978609503
GSE28863_A3Down-0.1535309506
GSE28863_A4Down-0.1763824737
GSE48662Down-0.1498036769

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-33a-5pMIMAT0000091MIRT049852CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.