HCSGD entry for SH3GLB1
1. General information
| Official gene symbol | SH3GLB1 |
|---|---|
| Entrez ID | 51100 |
| Gene full name | SH3-domain GRB2-like endophilin B1 |
| Other gene symbols | Bif-1 PPP1R70 dJ612B15.2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0005504 | Fatty acid binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005741 | Mitochondrial outer membrane | IEA | cellular_component |
| GO:0006654 | Phosphatidic acid biosynthetic process | IEA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0032461 | Positive regulation of protein oligomerization | IDA | biological_process |
| GO:0042171 | Lysophosphatidic acid acyltransferase activity | IEA | molecular_function |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0043234 | Protein complex | IEA | cellular_component |
| GO:0051084 | 'de novo' posttranslational protein folding | IEA | biological_process |
| GO:0051259 | Protein oligomerization | IDA | biological_process |
| GO:1900740 | Positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1261890278 | 0.8951229779 | 0.7242523768 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3137428079 |
| GSE13712_SHEAR | Down | -0.1885822441 |
| GSE13712_STATIC | Down | -0.1354147387 |
| GSE19018 | Up | 0.4813933164 |
| GSE19899_A1 | Up | 0.1047288475 |
| GSE19899_A2 | Down | -0.0185233635 |
| PubMed_21979375_A1 | Up | 0.0712515266 |
| PubMed_21979375_A2 | Down | -0.0906048530 |
| GSE35957 | Up | 0.2622786815 |
| GSE36640 | Up | 0.3721134362 |
| GSE54402 | Up | 0.3160345346 |
| GSE9593 | Up | 0.3261962146 |
| GSE43922 | Down | -0.0436652496 |
| GSE24585 | Down | -0.0033899753 |
| GSE37065 | Down | -0.0196509567 |
| GSE28863_A1 | Up | 0.4006122265 |
| GSE28863_A2 | Up | 0.7103333230 |
| GSE28863_A3 | Down | -0.0749892575 |
| GSE28863_A4 | Down | -0.3179880334 |
| GSE48662 | Up | 0.0105893930 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-29c-3p | MIMAT0000681 | MIRT020362 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT028134 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032399 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
