HCSGD entry for TRIM17
1. General information
| Official gene symbol | TRIM17 |
|---|---|
| Entrez ID | 51127 |
| Gene full name | tripartite motif containing 17 |
| Other gene symbols | RBCC RNF16 terf |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0005622 | Intracellular | IEA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0051865 | Protein autoubiquitination | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8573961134 | 0.5876214620 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0047482127 |
| GSE13712_SHEAR | Down | -0.0636529568 |
| GSE13712_STATIC | Up | 0.2054710602 |
| GSE19018 | Up | 0.0034048994 |
| GSE19899_A1 | Down | -0.0903242468 |
| GSE19899_A2 | Up | 0.1474059147 |
| PubMed_21979375_A1 | Down | -0.2845039669 |
| PubMed_21979375_A2 | Down | -0.0295027263 |
| GSE35957 | Down | -0.0172075552 |
| GSE36640 | Up | 0.1067878293 |
| GSE54402 | Down | -0.2266822192 |
| GSE9593 | Down | -0.1021152639 |
| GSE43922 | Up | 0.0768807801 |
| GSE24585 | Up | 0.1329958797 |
| GSE37065 | Down | -0.0250767366 |
| GSE28863_A1 | Down | -0.0601635784 |
| GSE28863_A2 | Down | -0.0439573223 |
| GSE28863_A3 | Up | 0.0810493217 |
| GSE28863_A4 | Down | -0.1224344047 |
| GSE48662 | Up | 0.0507339348 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029963 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 16778193 | Stable expression of each isoform, in a pml-null background, yields distinct subcellular localization patterns, suggesting that, like in other RBCC/TRIM proteins, the COOH-terminal domains of PML are involved in interactions with specific cellular components |
| 15000677 | Chromosome telomeres of humans and many model organisms contain a structure called a t-loop, which is maintained by TERF, TINF2, Pot1, and other proteins |
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