HCSGD entry for RLIM
1. General information
| Official gene symbol | RLIM |
|---|---|
| Entrez ID | 51132 |
| Gene full name | ring finger protein, LIM domain interacting |
| Other gene symbols | NY-REN-43 RNF12 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0003714 | Transcription corepressor activity | NAS | molecular_function |
| GO:0004842 | Ubiquitin-protein ligase activity | ISS | molecular_function |
| GO:0005634 | Nucleus | IDA ISS | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | ISS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016567 | Protein ubiquitination | ISS | biological_process |
| GO:0017053 | Transcriptional repressor complex | NAS | cellular_component |
| GO:0043433 | Negative regulation of sequence-specific DNA binding transcription factor activity | IEA | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | NAS | biological_process |
| GO:0060816 | Random inactivation of X chromosome | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5008305384 | 0.6638393450 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0587834067 |
| GSE13712_SHEAR | Up | 0.1045126011 |
| GSE13712_STATIC | Up | 0.0323061795 |
| GSE19018 | Down | -0.2548264733 |
| GSE19899_A1 | Up | 0.0165172752 |
| GSE19899_A2 | Up | 0.1039347052 |
| PubMed_21979375_A1 | Up | 0.3269795614 |
| PubMed_21979375_A2 | Up | 0.4266076910 |
| GSE35957 | Up | 0.2903326142 |
| GSE36640 | Down | -0.3907230984 |
| GSE54402 | Up | 0.0655478346 |
| GSE9593 | Up | 0.1634436165 |
| GSE43922 | Down | -0.0604114659 |
| GSE24585 | Down | -0.2405381759 |
| GSE37065 | Down | -0.2422291596 |
| GSE28863_A1 | Up | 0.1618653388 |
| GSE28863_A2 | Up | 0.1118364489 |
| GSE28863_A3 | Down | -0.1285805175 |
| GSE28863_A4 | Up | 0.0512825953 |
| GSE48662 | Up | 0.1809075544 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-186-5p | MIMAT0000456 | MIRT044990 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-15b-5p | MIMAT0000417 | MIRT046403 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047752 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048396 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
