HCSGD entry for EGFL7
1. General information
| Official gene symbol | EGFL7 |
|---|---|
| Entrez ID | 51162 |
| Gene full name | EGF-like-domain, multiple 7 |
| Other gene symbols | NEU1 RP11-251M1.2 VE-STATIN ZNEU1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | IEA | biological_process |
| GO:0001568 | Blood vessel development | ISS | biological_process |
| GO:0001570 | Vasculogenesis | IEA ISS | biological_process |
| GO:0001938 | Positive regulation of endothelial cell proliferation | IMP | biological_process |
| GO:0005112 | Notch binding | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | ISS | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0030336 | Negative regulation of cell migration | IEA | biological_process |
| GO:0045746 | Negative regulation of Notch signaling pathway | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1043022226 | 0.9583638198 | 0.6713456256 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0380798011 |
| GSE13712_SHEAR | Down | -0.2432924092 |
| GSE13712_STATIC | Up | 0.0247374818 |
| GSE19018 | Up | 0.2083580148 |
| GSE19899_A1 | Up | 0.1455224138 |
| GSE19899_A2 | Up | 0.5141192601 |
| PubMed_21979375_A1 | Up | 0.3163749592 |
| PubMed_21979375_A2 | Up | 0.3346524131 |
| GSE35957 | Up | 0.1339626024 |
| GSE36640 | Up | 0.0674505120 |
| GSE54402 | Up | 0.0465090334 |
| GSE9593 | Up | 0.3976824814 |
| GSE43922 | Up | 0.0564230348 |
| GSE24585 | Down | -0.0270574513 |
| GSE37065 | Down | -0.0184387699 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.3809381970 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-126-3p | MIMAT0000445 | MIRT006558 | Flow//Immunoblot//Immunohistochemistry//Luciferase reporter assay//qRT-PCR//Western blot//Western blot;qRT-PCR;Other | Functional MTI | 20034472 |
| hsa-miR-126-3p | MIMAT0000445 | MIRT006558 | Reporter assay | Non-Functional MTI | 21249429 |
| hsa-miR-133a-3p | MIMAT0000427 | MIRT021710 | Reporter assay | Non-Functional MTI | 21249429 |
| hsa-miR-361-5p | MIMAT0000703 | MIRT044066 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
