HCSGD entry for PLEKHO1

1. General information

Official gene symbolPLEKHO1
Entrez ID51177
Gene full namepleckstrin homology domain containing, family O member 1
Other gene symbolsCKIP-1 OC120
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.95506731130.01439390600.99999024730.2357573118

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.4761817014
GSE13712_SHEARUp0.1442640338
GSE13712_STATICUp0.1295478730
GSE19018Down-0.2126255677
GSE19899_A1Down-0.5813811921
GSE19899_A2Down-0.6852845369
PubMed_21979375_A1Up0.6319637608
PubMed_21979375_A2Down-0.4576169240
GSE35957Down-0.3587816114
GSE36640Down-1.3746226801
GSE54402Up0.3120694654
GSE9593Down-0.4122792473
GSE43922Up0.0843030748
GSE24585Down-0.1572918158
GSE37065Up0.0371773572
GSE28863_A1Down-0.0822810907
GSE28863_A2Down-0.2997115115
GSE28863_A3Down-0.4451243945
GSE28863_A4Down-0.2212297648
GSE48662Down-0.4811172217

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-149-5pMIMAT0000450MIRT045557CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.