HCSGD entry for PCOLCE

1. General information

Official gene symbolPCOLCE
Entrez ID5118
Gene full nameprocollagen C-endopeptidase enhancer
Other gene symbolsPCPE PCPE-1 PCPE1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005518Collagen bindingIDAmolecular_function
GO:0005615Extracellular spaceIDAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0007275Multicellular organismal developmentTASbiological_process
GO:0008201Heparin bindingIDAmolecular_function
GO:0010952Positive regulation of peptidase activityIDAbiological_process
GO:0016504Peptidase activator activityIDAmolecular_function
GO:0031012Extracellular matrixIDAcellular_component
GO:0043085Positive regulation of catalytic activityIDAbiological_process
GO:0050790Regulation of catalytic activityIDAbiological_process
GO:0052547Regulation of peptidase activityIDAbiological_process
GO:0070062Extracellular vesicular exosomeIDAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.73056896770.00034315950.99999024730.0339560150

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-1.8521921353
GSE13712_SHEARDown-0.1997652685
GSE13712_STATICDown-0.3890218857
GSE19018Down-0.9400288523
GSE19899_A1Down-1.5723013362
GSE19899_A2Down-2.1044319708
PubMed_21979375_A1Down-1.8227521832
PubMed_21979375_A2Down-2.4934932929
GSE35957Down-1.9823905149
GSE36640Down-3.1213597986
GSE54402Up0.1384222194
GSE9593Down-0.3589373635
GSE43922Down-0.9762752325
GSE24585Up0.5793097428
GSE37065Down-0.3591156281
GSE28863_A1Up0.8815254150
GSE28863_A2Up0.8340591767
GSE28863_A3Up0.3066582943
GSE28863_A4Down-0.2308298951
GSE48662Down-0.1733432184

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.