HCSGD entry for CLDN18
1. General information
| Official gene symbol | CLDN18 |
|---|---|
| Entrez ID | 51208 |
| Gene full name | claudin 18 |
| Other gene symbols | SFTA5 SFTPJ |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005198 | Structural molecule activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0005923 | Tight junction | IEA ISS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016338 | Calcium-independent cell-cell adhesion | ISS | biological_process |
| GO:0034329 | Cell junction assembly | TAS | biological_process |
| GO:0042802 | Identical protein binding | ISS | molecular_function |
| GO:0045216 | Cell-cell junction organization | TAS | biological_process |
| GO:0070830 | Tight junction assembly | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9439570267 | 0.4909712853 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0471025822 |
| GSE13712_SHEAR | Up | 0.0708708429 |
| GSE13712_STATIC | Down | -0.0307650946 |
| GSE19018 | Down | -0.0184298301 |
| GSE19899_A1 | Up | 0.0179565709 |
| GSE19899_A2 | Down | -0.0628560592 |
| PubMed_21979375_A1 | Down | -0.2109342150 |
| PubMed_21979375_A2 | Down | -0.0817963250 |
| GSE35957 | Up | 0.1041754646 |
| GSE36640 | Down | -0.2926472909 |
| GSE54402 | Down | -0.0412828647 |
| GSE9593 | Up | 0.0375396438 |
| GSE43922 | Up | 0.0136821072 |
| GSE24585 | Down | -0.0238285562 |
| GSE37065 | Down | -0.1550411670 |
| GSE28863_A1 | Down | -0.1531155546 |
| GSE28863_A2 | Down | -0.1333061753 |
| GSE28863_A3 | Up | 0.0211113462 |
| GSE28863_A4 | Up | 0.1457685783 |
| GSE48662 | Down | -0.0196320730 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
