HCSGD entry for MZB1


1. General information

Official gene symbolMZB1
Entrez ID51237
Gene full namemarginal zone B and B1 cell-specific protein
Other gene symbolsMEDA-7 PACAP pERp1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002642Positive regulation of immunoglobulin biosynthetic processISSbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIDA IEAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005788Endoplasmic reticulum lumenISScellular_component
GO:0006915Apoptotic processIEAbiological_process
GO:0008284Positive regulation of cell proliferationIDA IEAbiological_process
GO:0030888Regulation of B cell proliferationISSbiological_process
GO:0033622Integrin activationISSbiological_process
GO:0034663Endoplasmic reticulum chaperone complexISScellular_component
GO:0042127Regulation of cell proliferationISSbiological_process
GO:2001274Negative regulation of glucose import in response to insulin stimulusISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.80338553250.55554662440.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0066863827
GSE13712_SHEARDown-0.0066655955
GSE13712_STATICUp0.0520752329
GSE19018Up0.0185579622
GSE19899_A1Down-0.1508708976
GSE19899_A2Up0.1771794359
PubMed_21979375_A1Down-0.0698628482
PubMed_21979375_A2Down-0.1255103068
GSE35957Down-0.0447933931
GSE36640Up0.0167188430
GSE54402Up0.0048190627
GSE9593Up0.1873204712
GSE43922Up0.1345412239
GSE24585Down-0.0465721895
GSE37065Down-0.0777938156
GSE28863_A1Down-0.3132286647
GSE28863_A2Down-0.2622889210
GSE28863_A3Up0.1944261402
GSE28863_A4Up0.1880468754
GSE48662Up0.0668793495

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.