HCSGD entry for SPG21
1. General information
| Official gene symbol | SPG21 |
|---|---|
| Entrez ID | 51324 |
| Gene full name | spastic paraplegia 21 (autosomal recessive, Mast syndrome) |
| Other gene symbols | ACP33 GL010 MASPARDIN MAST |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0010008 | Endosome membrane | IEA | cellular_component |
| GO:0030140 | Trans-Golgi network transport vesicle | IDA | cellular_component |
| GO:0042609 | CD4 receptor binding | IPI | molecular_function |
| GO:0050851 | Antigen receptor-mediated signaling pathway | IC | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4104739600 | 0.6856285286 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3462675752 |
| GSE13712_SHEAR | Down | -0.1730448061 |
| GSE13712_STATIC | Down | -0.0716357646 |
| GSE19018 | Up | 0.3162188043 |
| GSE19899_A1 | Up | 0.0000170169 |
| GSE19899_A2 | Up | 0.0320741255 |
| PubMed_21979375_A1 | Down | -0.2917297581 |
| PubMed_21979375_A2 | Up | 0.2152776893 |
| GSE35957 | Up | 0.1134818645 |
| GSE36640 | Down | -0.1336726420 |
| GSE54402 | Up | 0.3162845345 |
| GSE9593 | Down | -0.0759551135 |
| GSE43922 | Up | 0.0016915677 |
| GSE24585 | Down | -0.3473941932 |
| GSE37065 | Up | 0.0433363277 |
| GSE28863_A1 | Up | 0.3161275802 |
| GSE28863_A2 | Up | 0.3047408134 |
| GSE28863_A3 | Down | -0.2684714698 |
| GSE28863_A4 | Up | 0.0901307889 |
| GSE48662 | Down | -0.2114487392 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
