HCSGD entry for ANGPT4

1. General information

Official gene symbolANGPT4
Entrez ID51378
Gene full nameangiopoietin 4
Other gene symbolsAGP4 ANG-3 ANG4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001525AngiogenesisIEAbiological_process
GO:0001935Endothelial cell proliferationIDAbiological_process
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIDAcellular_component
GO:0007171Activation of transmembrane receptor protein tyrosine kinase activityIDAbiological_process
GO:0007596Blood coagulationTASbiological_process
GO:0010469Regulation of receptor activityIDAbiological_process
GO:0010595Positive regulation of endothelial cell migrationIDAbiological_process
GO:0016525Negative regulation of angiogenesisIDAbiological_process
GO:0030297Transmembrane receptor protein tyrosine kinase activator activityIDAmolecular_function
GO:0030971Receptor tyrosine kinase bindingIDAmolecular_function
GO:0043066Negative regulation of apoptotic processIDAbiological_process
GO:0043085Positive regulation of catalytic activityIDAbiological_process
GO:0043536Positive regulation of blood vessel endothelial cell migrationIDAbiological_process
GO:0043537Negative regulation of blood vessel endothelial cell migrationIDAbiological_process
GO:0045766Positive regulation of angiogenesisIDAbiological_process
GO:0045859Regulation of protein kinase activityIDAbiological_process
GO:0045860Positive regulation of protein kinase activityIDAbiological_process
GO:0050731Positive regulation of peptidyl-tyrosine phosphorylationIDAbiological_process
GO:0050790Regulation of catalytic activityIDAbiological_process
GO:0050900Leukocyte migrationTASbiological_process
GO:0061098Positive regulation of protein tyrosine kinase activityIDAbiological_process
GO:0071456Cellular response to hypoxiaIEPbiological_process
GO:2000273Positive regulation of receptor activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.21900237070.91881402680.90025947211.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1585274010
GSE13712_SHEARDown-0.1014541602
GSE13712_STATICUp0.0213472011
GSE19018Down-0.0233850401
GSE19899_A1Down-0.0402357463
GSE19899_A2Down-0.0136172576
PubMed_21979375_A1Up0.2803079089
PubMed_21979375_A2Down-0.0318159311
GSE35957Up0.2526141917
GSE36640Down-0.1153602804
GSE54402Up0.0518931002
GSE9593Up0.1427669692
GSE43922Up0.0677274719
GSE24585Up0.0296280415
GSE37065Up0.0508525327
GSE28863_A1Up0.2432387371
GSE28863_A2Up0.3563631936
GSE28863_A3Up0.2947078588
GSE28863_A4Up0.0060797530
GSE48662Up0.9362628271

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT016991MicroarrayFunctional MTI (Weak)18185580
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.