HCSGD entry for PDE6C
1. General information
| Official gene symbol | PDE6C |
|---|---|
| Entrez ID | 5146 |
| Gene full name | phosphodiesterase 6C, cGMP-specific, cone, alpha prime |
| Other gene symbols | ACHM5 COD4 PDEA2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0007601 | Visual perception | IEA | biological_process |
| GO:0007603 | Phototransduction, visible light | IEA | biological_process |
| GO:0030553 | CGMP binding | IEA | molecular_function |
| GO:0046549 | Retinal cone cell development | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7577470119 | 0.7433321074 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0237973817 |
| GSE13712_SHEAR | Down | -0.1558936726 |
| GSE13712_STATIC | Up | 0.1445330889 |
| GSE19018 | Up | 0.0167458668 |
| GSE19899_A1 | Up | 0.0557356607 |
| GSE19899_A2 | Down | -0.2552474092 |
| PubMed_21979375_A1 | Down | -0.1516049802 |
| PubMed_21979375_A2 | Down | -0.1211824797 |
| GSE35957 | Up | 0.0644253009 |
| GSE36640 | Down | -0.0192281767 |
| GSE54402 | Up | 0.2503287649 |
| GSE9593 | Down | -0.0506312072 |
| GSE43922 | Up | 0.0194052339 |
| GSE24585 | Up | 0.1707593690 |
| GSE37065 | Down | -0.0318505323 |
| GSE28863_A1 | Up | 0.0422165578 |
| GSE28863_A2 | Up | 0.0403717440 |
| GSE28863_A3 | Up | 0.1144476165 |
| GSE28863_A4 | Down | -0.0450966213 |
| GSE48662 | Up | 0.0546624699 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
