HCSGD entry for EVL
1. General information
| Official gene symbol | EVL |
|---|---|
| Entrez ID | 51466 |
| Gene full name | Enah/Vasp-like |
| Other gene symbols | RNB6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003779 | Actin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005522 | Profilin binding | IEA ISS | molecular_function |
| GO:0005737 | Cytoplasm | IEA ISS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0005925 | Focal adhesion | IEA ISS | cellular_component |
| GO:0007015 | Actin filament organization | TAS | biological_process |
| GO:0007166 | Cell surface receptor signaling pathway | NAS | biological_process |
| GO:0007399 | Nervous system development | NAS | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0008154 | Actin polymerization or depolymerization | ISS | biological_process |
| GO:0009887 | Organ morphogenesis | NAS | biological_process |
| GO:0017124 | SH3 domain binding | ISS | molecular_function |
| GO:0030027 | Lamellipodium | IEA ISS | cellular_component |
| GO:0051289 | Protein homotetramerization | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9895409863 | 0.0125647240 | 0.9999902473 | 0.2210669118 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4937729068 |
| GSE13712_SHEAR | Down | -0.5013377948 |
| GSE13712_STATIC | Down | -0.2498585679 |
| GSE19018 | Down | -0.1721478058 |
| GSE19899_A1 | Down | -0.2965529152 |
| GSE19899_A2 | Down | -1.6853013527 |
| PubMed_21979375_A1 | Down | -0.7552979314 |
| PubMed_21979375_A2 | Down | -0.7724111023 |
| GSE35957 | Down | -0.1830585681 |
| GSE36640 | Down | -0.1982340358 |
| GSE54402 | Down | -0.6497099455 |
| GSE9593 | Down | -0.0640221131 |
| GSE43922 | Down | -0.2747693549 |
| GSE24585 | Down | -0.1730325539 |
| GSE37065 | Down | -0.2013377031 |
| GSE28863_A1 | Down | -0.0175754934 |
| GSE28863_A2 | Up | 0.0966187477 |
| GSE28863_A3 | Up | 0.3300918840 |
| GSE28863_A4 | Down | -0.0129147403 |
| GSE48662 | Up | 0.1279081636 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-221-3p | MIMAT0000278 | MIRT046908 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
