HCSGD entry for PDE7A


1. General information

Official gene symbolPDE7A
Entrez ID5150
Gene full namephosphodiesterase 7A
Other gene symbolsHCP1 PDE7
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:00041153',5'-cyclic-AMP phosphodiesterase activityIDA TASmolecular_function
GO:0005829CytosolTAScellular_component
GO:0006198CAMP catabolic processIEAbiological_process
GO:0007165Signal transductionIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.98000986280.04296397170.99999024730.3900844084

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1304930867
GSE13712_SHEARDown-0.0666230770
GSE13712_STATICDown-0.0288968508
GSE19018Down-0.0326059699
GSE19899_A1Down-0.1249469034
GSE19899_A2Down-0.7218035991
PubMed_21979375_A1Down-0.6547280798
PubMed_21979375_A2Down-0.4901076730
GSE35957Down-0.3171161564
GSE36640Down-1.1082462006
GSE54402Down-0.1183525208
GSE9593Down-0.5442833748
GSE43922Down-0.2078920188
GSE24585Down-0.0785054973
GSE37065Up0.0077382786
GSE28863_A1Up0.4683120212
GSE28863_A2Up0.1558367281
GSE28863_A3Down-0.2049721846
GSE28863_A4Down-0.0043912533
GSE48662Down-0.0054920101

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

KetotifenDB00920 APRD01061
3-isobutyl-1-methyl-7H-xanthineDB07954 -
3-(2,6-difluorophenyl)-2-(methylthio)quinazolin-4(3H)-oneDB08602 -

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.