HCSGD entry for MST4

1. General information

Official gene symbolMST4
Entrez ID51765
Gene full nameserine/threonine protein kinase MST4
Other gene symbolsMASK
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneIEAcellular_component
GO:0000287Magnesium ion bindingIDAmolecular_function
GO:0004672Protein kinase activityIDA IEAmolecular_function
GO:0004702Receptor signaling protein serine/threonine kinase activityIBAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIDA IEAmolecular_function
GO:0005737CytoplasmIBAcellular_component
GO:0005829CytosolTAScellular_component
GO:0006468Protein phosphorylationIDAbiological_process
GO:0006915Apoptotic processTASbiological_process
GO:0006921Cellular component disassembly involved in execution phase of apoptosisTASbiological_process
GO:0007165Signal transductionIBAbiological_process
GO:0023014Signal transduction by phosphorylationIBAbiological_process
GO:0035556Intracellular signal transductionIBAbiological_process
GO:0042802Identical protein bindingIPImolecular_function
GO:0042981Regulation of apoptotic processIDAbiological_process
GO:0045595Regulation of cell differentiationIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.81706035110.04036520270.99999024730.3791764811

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1887545664
GSE13712_SHEARUp0.2572351617
GSE13712_STATICUp0.5856243021
GSE19018Down-0.2322652125
GSE19899_A1Up0.1848393879
GSE19899_A2Up0.1832982446
PubMed_21979375_A1Up0.3764884656
PubMed_21979375_A2Down-0.2791678203
GSE35957Down-2.6938043564
GSE36640Down-0.8913056655
GSE54402Down-0.0354286524
GSE9593Down-0.4381362053
GSE43922Up0.0155728776
GSE24585Down-0.0497592109
GSE37065Down-0.0353020858
GSE28863_A1Down-0.3789414188
GSE28863_A2Down-0.2757333049
GSE28863_A3Up0.0801596809
GSE28863_A4Down-0.0612543804
GSE48662Down-0.2408358427

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

[4-({4-[(5-CYCLOPROPYL-1H-PYRAZOL-3-YL)AMINO]QUINAZOLIN-2-YL}IMINO)CYCLOHEXA-2,5-DIEN-1-YL]ACETONITRILEDB07853 -

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022711MicroarrayFunctional MTI (Weak)18668037
hsa-miR-26b-5pMIMAT0000083MIRT029545MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.