HCSGD entry for ZAK

1. General information

Official gene symbolZAK
Entrez ID51776
Gene full namesterile alpha motif and leucine zipper containing kinase AZK
Other gene symbolsAZK MLK7 MLT MLTK MRK mlklak pk
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000287Magnesium ion bindingIEAmolecular_function
GO:0004709MAP kinase kinase kinase activityIEAmolecular_function
GO:0005524ATP bindingIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIDA IEAcellular_component
GO:0007010Cytoskeleton organizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.95730613960.04397448430.99999024730.3944324702

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1666706903
GSE13712_SHEARDown-0.2582133023
GSE13712_STATICDown-0.1557670235
GSE19018Up0.1224244557
GSE19899_A1Down-0.3580413550
GSE19899_A2Up0.1020076200
PubMed_21979375_A1Up0.1714921408
PubMed_21979375_A2Up0.0334002058
GSE35957Up0.1594601227
GSE36640Down-0.2178442037
GSE54402Down-0.0122875277
GSE9593Down-0.5147055408
GSE43922Down-0.0429131462
GSE24585Down-0.3752830838
GSE37065Down-0.1757151199
GSE28863_A1Up0.2564469117
GSE28863_A2Up0.0080244317
GSE28863_A3Down-1.1844130585
GSE28863_A4Down-0.0541576537
GSE48662Down-0.1617793720

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.