HCSGD entry for ATP6V1B1

1. General information

Official gene symbolATP6V1B1
Entrez ID525
Gene full nameATPase, H+ transporting, lysosomal 56/58kDa, V1 subunit B1
Other gene symbolsATP6B1 RTA1B VATB VMA2 VPP3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001503OssificationIMPbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0005737CytoplasmISScellular_component
GO:0005829CytosolIEA TAScellular_component
GO:0005902MicrovillusIEA ISScellular_component
GO:0006879Cellular iron ion homeostasisTASbiological_process
GO:0006885Regulation of pHIEA IMPbiological_process
GO:0007588ExcretionIMPbiological_process
GO:0007605Sensory perception of soundIMPbiological_process
GO:0008286Insulin receptor signaling pathwayTASbiological_process
GO:0012505Endomembrane systemIEAcellular_component
GO:0015078Hydrogen ion transmembrane transporter activityIEA ISSmolecular_function
GO:0015991ATP hydrolysis coupled proton transportIEAbiological_process
GO:0015992Proton transportIEA IMPbiological_process
GO:0016323Basolateral plasma membraneIEA ISScellular_component
GO:0016324Apical plasma membraneIDA IEAcellular_component
GO:0016328Lateral plasma membraneIEA ISScellular_component
GO:0016471Vacuolar proton-transporting V-type ATPase complexIMPcellular_component
GO:0016820Hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substancesIEAmolecular_function
GO:0032403Protein complex bindingIEAmolecular_function
GO:0033178Proton-transporting two-sector ATPase complex, catalytic domainIEAcellular_component
GO:0033180Proton-transporting V-type ATPase, V1 domainIEAcellular_component
GO:0033572Transferrin transportTASbiological_process
GO:0042472Inner ear morphogenesisIMPbiological_process
GO:0045851PH reductionIMPbiological_process
GO:0046034ATP metabolic processIEAbiological_process
GO:0051701Interaction with hostTASbiological_process
GO:0055074Calcium ion homeostasisIMPbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0090382Phagosome maturationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.91729718860.52854041640.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0236442141
GSE13712_SHEARDown-0.0335035295
GSE13712_STATICUp0.0277733700
GSE19018Down-0.0570018234
GSE19899_A1Down-0.1274229536
GSE19899_A2Down-0.0528008202
PubMed_21979375_A1Down-0.1948462906
PubMed_21979375_A2Down-0.0859800035
GSE35957Up0.1076832602
GSE36640Up0.1096117828
GSE54402Down-0.0799980586
GSE9593Down-0.1177466201
GSE43922Up0.0396873710
GSE24585Down-0.1216242702
GSE37065Down-0.1005490956
GSE28863_A1Up0.0000840094
GSE28863_A2Up0.0692622520
GSE28863_A3Up0.2203852595
GSE28863_A4Up0.0223154419
GSE48662Down-0.1051496425

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.