HCSGD entry for PHKB
1. General information
| Official gene symbol | PHKB |
|---|---|
| Entrez ID | 5257 |
| Gene full name | phosphorylase kinase, beta |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004553 | Hydrolase activity, hydrolyzing O-glycosyl compounds | IEA | molecular_function |
| GO:0004689 | Phosphorylase kinase activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005516 | Calmodulin binding | IEA | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0005964 | Phosphorylase kinase complex | IEA | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0005977 | Glycogen metabolic process | IEA TAS | biological_process |
| GO:0005980 | Glycogen catabolic process | TAS | biological_process |
| GO:0006006 | Glucose metabolic process | TAS | biological_process |
| GO:0006091 | Generation of precursor metabolites and energy | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6855394894 | 0.0080573268 | 0.9999902473 | 0.1786663016 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2373903506 |
| GSE13712_SHEAR | Down | -0.1420119327 |
| GSE13712_STATIC | Down | -0.1698792386 |
| GSE19018 | Up | 0.4704673852 |
| GSE19899_A1 | Down | -1.2280778963 |
| GSE19899_A2 | Down | -1.1316129340 |
| PubMed_21979375_A1 | Down | -2.2184484187 |
| PubMed_21979375_A2 | Down | -1.7575003097 |
| GSE35957 | Up | 0.3581651225 |
| GSE36640 | Up | 0.2710659421 |
| GSE54402 | Down | -0.7759424545 |
| GSE9593 | Up | 0.3266114295 |
| GSE43922 | Down | -1.2924558402 |
| GSE24585 | Up | 0.2607430215 |
| GSE37065 | Down | -0.1459801545 |
| GSE28863_A1 | Up | 0.3059236610 |
| GSE28863_A2 | Up | 0.2813040728 |
| GSE28863_A3 | Down | -0.7838988834 |
| GSE28863_A4 | Up | 0.2027649605 |
| GSE48662 | Down | -0.2978501863 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT000889 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT000890 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-484 | MIMAT0002174 | MIRT041947 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-15a-5p | MIMAT0000068 | NA | hsa-miR-15a | 18362358 | |||
| hsa-miR-16-5p | MIMAT0000069 | NA | hsa-miR-16 | 18362358 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
