HCSGD entry for ATP6V0C

1. General information

Official gene symbolATP6V0C
Entrez ID527
Gene full nameATPase, H+ transporting, lysosomal 16kDa, V0 subunit c
Other gene symbolsATP6C ATP6L ATPL VATL VPPC Vma3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005765Lysosomal membraneIDAcellular_component
GO:0006200ATP catabolic processTASbiological_process
GO:0006879Cellular iron ion homeostasisTASbiological_process
GO:0008152Metabolic processTASbiological_process
GO:0008286Insulin receptor signaling pathwayTASbiological_process
GO:0010008Endosome membraneTAScellular_component
GO:0015078Hydrogen ion transmembrane transporter activityIEAmolecular_function
GO:0015991ATP hydrolysis coupled proton transportIEAbiological_process
GO:0015992Proton transportTASbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016032Viral processIEAbiological_process
GO:0030670Phagocytic vesicle membraneTAScellular_component
GO:0031625Ubiquitin protein ligase bindingIPImolecular_function
GO:0033179Proton-transporting V-type ATPase, V0 domainIEAcellular_component
GO:0033572Transferrin transportTASbiological_process
GO:0046933Proton-transporting ATP synthase activity, rotational mechanismTASmolecular_function
GO:0046961Proton-transporting ATPase activity, rotational mechanismTASmolecular_function
GO:0051701Interaction with hostTASbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0090382Phagosome maturationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00318404700.99815509670.15182481881.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.7335196586
GSE13712_SHEARUp0.3318411980
GSE13712_STATICUp0.3040376285
GSE19018Up0.3762175670
GSE19899_A1Up0.5092344463
GSE19899_A2Up1.5784121736
PubMed_21979375_A1Up0.9591571829
PubMed_21979375_A2Up1.2344145472
GSE35957Down-0.0953577461
GSE36640Up0.8994199308
GSE54402Up0.4868030487
GSE9593Up0.4810620559
GSE43922Up0.4667120763
GSE24585Up0.1303893337
GSE37065Up0.0025116075
GSE28863_A1Down-0.0065344712
GSE28863_A2Up0.2720675138
GSE28863_A3Up0.1371662837
GSE28863_A4Up0.0101529787
GSE48662Up0.0166131697

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-421MIMAT0003339MIRT039438CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.