HCSGD entry for SERPINI2


1. General information

Official gene symbolSERPINI2
Entrez ID5276
Gene full nameserpin peptidase inhibitor, clade I (pancpin), member 2
Other gene symbolsMEPI PANCPIN PI14 TSA2004
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004867Serine-type endopeptidase inhibitor activityIBA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005615Extracellular spaceIEAcellular_component
GO:0006928Cellular component movementTASbiological_process
GO:0010951Negative regulation of endopeptidase activityIBAbiological_process
GO:0030155Regulation of cell adhesionIEAbiological_process
GO:0030162Regulation of proteolysisIBAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.77187016450.84412013220.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0976126381
GSE13712_SHEARDown-0.0303612198
GSE13712_STATICUp0.0852638238
GSE19018Up0.0854586544
GSE19899_A1Up0.0804538413
GSE19899_A2Up0.0496003505
PubMed_21979375_A1Down-0.1221391852
PubMed_21979375_A2Up0.0024983730
GSE35957Up0.1978592444
GSE36640Down-0.0254586340
GSE54402Up0.0416524573
GSE9593Up0.0614797216
GSE43922Up0.0188345398
GSE24585Up0.0836058730
GSE37065Down-0.0376568624
GSE28863_A1Up0.0012458446
GSE28863_A2Up0.0771237495
GSE28863_A3Up0.0001957138
GSE28863_A4Down-0.0090633269
GSE48662Up0.0171124414

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029774MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.