HCSGD entry for ZFYVE1
1. General information
| Official gene symbol | ZFYVE1 |
|---|---|
| Entrez ID | 53349 |
| Gene full name | zinc finger, FYVE domain containing 1 |
| Other gene symbols | DFCP1 TAFF1 ZNFN2A1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005545 | 1-phosphatidylinositol binding | IDA | molecular_function |
| GO:0005547 | Phosphatidylinositol-3,4,5-trisphosphate binding | IDA | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005795 | Golgi stack | IDA | cellular_component |
| GO:0008270 | Zinc ion binding | NAS | molecular_function |
| GO:0010923 | Negative regulation of phosphatase activity | IDA | biological_process |
| GO:0043325 | Phosphatidylinositol-3,4-bisphosphate binding | IDA | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0083090004 | 0.9804015197 | 0.2358337284 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4110936215 |
| GSE13712_SHEAR | Down | -0.0229092051 |
| GSE13712_STATIC | Up | 0.0568751812 |
| GSE19018 | Up | 0.1574455829 |
| GSE19899_A1 | Up | 0.2630020507 |
| GSE19899_A2 | Up | 0.3254662649 |
| PubMed_21979375_A1 | Up | 0.5419001900 |
| PubMed_21979375_A2 | Up | 1.5335298765 |
| GSE35957 | Down | -0.0387833614 |
| GSE36640 | Up | 0.6793443833 |
| GSE54402 | Down | -0.0037969704 |
| GSE9593 | Up | 0.9234721606 |
| GSE43922 | Up | 0.2962218136 |
| GSE24585 | Up | 1.0843425841 |
| GSE37065 | Down | -0.0227791325 |
| GSE28863_A1 | Up | 0.3577659212 |
| GSE28863_A2 | Up | 0.3614210694 |
| GSE28863_A3 | Down | -0.5785891816 |
| GSE28863_A4 | Down | -0.0487527497 |
| GSE48662 | Up | 0.3497074192 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018968 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-125b-5p | MIMAT0000423 | MIRT046077 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
