HCSGD entry for PLXNA2

1. General information

Official gene symbolPLXNA2
Entrez ID5362
Gene full nameplexin A2
Other gene symbolsOCT PLXN2
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001756SomitogenesisIEAbiological_process
GO:0002116Semaphorin receptor complexTAScellular_component
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneISScellular_component
GO:0007411Axon guidanceTASbiological_process
GO:0017154Semaphorin receptor activityISSmolecular_function
GO:0021915Neural tube developmentIEAbiological_process
GO:0021935Cerebellar granule cell precursor tangential migrationIEAbiological_process
GO:0030334Regulation of cell migrationISSbiological_process
GO:0051642Centrosome localizationIEAbiological_process
GO:0060037Pharyngeal system developmentIEAbiological_process
GO:0060174Limb bud formationIEAbiological_process
GO:0071526Semaphorin-plexin signaling pathwayISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00523852820.88690934240.18885595081.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1447613858
GSE13712_SHEARUp0.7725978944
GSE13712_STATICUp0.8523151902
GSE19018Up0.1077445178
GSE19899_A1Up0.0736277184
GSE19899_A2Up0.9879845134
PubMed_21979375_A1Up0.8211755087
PubMed_21979375_A2Up0.3090197739
GSE35957Down-0.0878732535
GSE36640Up0.5348841988
GSE54402Up0.3440799089
GSE9593Down-0.5110530429
GSE43922Up0.8757542304
GSE24585Down-1.0696266367
GSE37065Up0.7237905390
GSE28863_A1Up0.5264833692
GSE28863_A2Up0.2740407029
GSE28863_A3Down-0.0675585733
GSE28863_A4Up0.3510771286
GSE48662Up0.0794228170

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT023176MicroarrayFunctional MTI (Weak)18668037
hsa-miR-26b-5pMIMAT0000083MIRT030349MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.