HCSGD entry for ATP5O

1. General information

Official gene symbolATP5O
Entrez ID539
Gene full nameATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
Other gene symbolsATPO OSCP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005215Transporter activityNASmolecular_function
GO:0005739MitochondrionIDAcellular_component
GO:0005743Mitochondrial inner membraneTAScellular_component
GO:0005753Mitochondrial proton-transporting ATP synthase complexIDA NAScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006200ATP catabolic processIDAbiological_process
GO:0006754ATP biosynthetic processNASbiological_process
GO:0008144Drug bindingIDAmolecular_function
GO:0015986ATP synthesis coupled proton transportIEAbiological_process
GO:0015992Proton transportNASbiological_process
GO:0016887ATPase activityIDAmolecular_function
GO:0022857Transmembrane transporter activityICmolecular_function
GO:0022904Respiratory electron transport chainTASbiological_process
GO:0042776Mitochondrial ATP synthesis coupled proton transportIMP TASbiological_process
GO:0044237Cellular metabolic processTASbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0046933Proton-transporting ATP synthase activity, rotational mechanismIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.71613646900.73441624180.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0572111689
GSE13712_SHEARDown-0.0814667006
GSE13712_STATICDown-0.0373310735
GSE19018Up0.3597449404
GSE19899_A1Up0.2025819227
GSE19899_A2Up0.1353453965
PubMed_21979375_A1Up0.1498423526
PubMed_21979375_A2Up0.3670250629
GSE35957Down-0.0607911750
GSE36640Down-0.0955747900
GSE54402Up0.0029712193
GSE9593Down-0.1542326179
GSE43922Down-0.0107593100
GSE24585Up0.0059782258
GSE37065Down-0.1296271491
GSE28863_A1Down-0.0521343133
GSE28863_A2Up0.0691178132
GSE28863_A3Down-0.1306572548
GSE28863_A4Up0.1277830093
GSE48662Down-0.2059766187

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-877-5pMIMAT0004949MIRT037315CLASHFunctional MTI (Weak)23622248
hsa-miR-30e-5pMIMAT0000692MIRT044151CLASHFunctional MTI (Weak)23622248
hsa-miR-182-5pMIMAT0000259MIRT047203CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.