HCSGD entry for DPM3


1. General information

Official gene symbolDPM3
Entrez ID54344
Gene full namedolichyl-phosphate mannosyltransferase polypeptide 3
Other gene symbolsCDG1O
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004582Dolichyl-phosphate beta-D-mannosyltransferase activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005789Endoplasmic reticulum membraneTAScellular_component
GO:0005975Carbohydrate metabolic processNASbiological_process
GO:0006488Dolichol-linked oligosaccharide biosynthetic processTASbiological_process
GO:0006501C-terminal protein lipidationTASbiological_process
GO:0006506GPI anchor biosynthetic processIDA TASbiological_process
GO:0018279Protein N-linked glycosylation via asparagineTASbiological_process
GO:0018406Protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophanTASbiological_process
GO:0030176Integral component of endoplasmic reticulum membraneIDAcellular_component
GO:0031501Mannosyltransferase complexTAScellular_component
GO:0031647Regulation of protein stabilityIPIbiological_process
GO:0033185Dolichol-phosphate-mannose synthase complexIDAcellular_component
GO:0035268Protein mannosylationTASbiological_process
GO:0035269Protein O-linked mannosylationTASbiological_process
GO:0043687Post-translational protein modificationTASbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00851721060.60732625280.23701782701.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.7501503864
GSE13712_SHEARDown-0.1368508543
GSE13712_STATICUp0.1063694141
GSE19018Up0.1616758159
GSE19899_A1Up0.4246760164
GSE19899_A2Up1.5657324111
PubMed_21979375_A1Up1.9591964399
PubMed_21979375_A2Up2.4256552997
GSE35957Down-0.5658794164
GSE36640Up1.1589604154
GSE54402Up0.5774737377
GSE9593Down-0.0895075749
GSE43922Up0.0055174520
GSE24585Down-0.0487832272
GSE37065Up0.1261147352
GSE28863_A1Down-0.7105109357
GSE28863_A2Down-0.2089747798
GSE28863_A3Down-0.3650163870
GSE28863_A4Down-0.0952345295
GSE48662Up0.6239121037

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-615-3pMIMAT0003283MIRT040333CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.