HCSGD entry for POLR2I

1. General information

Official gene symbolPOLR2I
Entrez ID5438
Gene full namepolymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa
Other gene symbolsRPB9 hRPB14.5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000398MRNA splicing, via spliceosomeTASbiological_process
GO:0001193Maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoterIBAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0003899DNA-directed RNA polymerase activityIBA IEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005665DNA-directed RNA polymerase II, core complexIDAcellular_component
GO:0006281DNA repairTASbiological_process
GO:0006283Transcription-coupled nucleotide-excision repairIBA TASbiological_process
GO:0006289Nucleotide-excision repairTASbiological_process
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006366Transcription from RNA polymerase II promoterIDA TASbiological_process
GO:0006367Transcription initiation from RNA polymerase II promoterIBA TASbiological_process
GO:0006368Transcription elongation from RNA polymerase II promoterTASbiological_process
GO:00063707-methylguanosine mRNA cappingTASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0008380RNA splicingTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016032Viral processTASbiological_process
GO:0050434Positive regulation of viral transcriptionTASbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97007706770.01919610960.99999024730.2708311064

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2668083503
GSE13712_SHEARDown-0.6599877760
GSE13712_STATICDown-0.4204283005
GSE19018Up0.0462444979
GSE19899_A1Down-0.8785619636
GSE19899_A2Down-0.3770267425
PubMed_21979375_A1Up0.7194758933
PubMed_21979375_A2Down-0.3945634084
GSE35957Down-0.5350000541
GSE36640Down-0.6934815323
GSE54402Up0.0957333657
GSE9593Down-0.3122033187
GSE43922Up0.0282220671
GSE24585Down-0.3633396916
GSE37065Down-0.0685009458
GSE28863_A1Down-0.2839621754
GSE28863_A2Down-0.4576869113
GSE28863_A3Down-0.0728477459
GSE28863_A4Up0.0763472775
GSE48662Down-0.0644540731

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT023875ProteomicsFunctional MTI (Weak)18668040
hsa-miR-1268aMIMAT0005922MIRT035845CLASHFunctional MTI (Weak)23622248
hsa-miR-1180-3pMIMAT0005825MIRT035955CLASHFunctional MTI (Weak)23622248
hsa-miR-328-3pMIMAT0000752MIRT043800CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049323CLASHFunctional MTI (Weak)23622248
Entries Per Page
Displaying Page of
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.