HCSGD entry for MTRF1L


1. General information

Official gene symbolMTRF1L
Entrez ID54516
Gene full namemitochondrial translational release factor 1-like
Other gene symbolsHMRF1L MRF1L mtRF1a
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003747Translation release factor activityIEAmolecular_function
GO:0005739MitochondrionIDAcellular_component
GO:0016149Translation release factor activity, codon specificIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15258370500.76572182290.77985008721.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3243602487
GSE13712_SHEARUp0.3849361890
GSE13712_STATICUp0.1661099109
GSE19018Down-0.2220440418
GSE19899_A1Up0.1845054025
GSE19899_A2Up0.3590203823
PubMed_21979375_A1Up0.2427130926
PubMed_21979375_A2Up0.5060821550
GSE35957Down-0.1492735896
GSE36640Down-0.3309855489
GSE54402Up0.2374807370
GSE9593Down-0.0660221187
GSE43922Up0.2386796735
GSE24585Down-0.7003934322
GSE37065Down-0.0062193628
GSE28863_A1Down-0.0392148889
GSE28863_A2Up0.0338586984
GSE28863_A3Up0.0678629974
GSE28863_A4Up0.2191920518
GSE48662Down-0.1707201493

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-125b-5pMIMAT0000423MIRT046047CLASHFunctional MTI (Weak)23622248
hsa-miR-196a-5pMIMAT0000226MIRT048201CLASHFunctional MTI (Weak)23622248
hsa-miR-26a-5pMIMAT0000082MIRT050099CLASHFunctional MTI (Weak)23622248
hsa-miR-17-5pMIMAT0000070MIRT050842CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.