HCSGD entry for SEMA4C
1. General information
| Official gene symbol | SEMA4C |
|---|---|
| Entrez ID | 54910 |
| Gene full name | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C |
| Other gene symbols | M-SEMA-F SEMACL1 SEMAF SEMAI |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001843 | Neural tube closure | IEA ISS | biological_process |
| GO:0004872 | Receptor activity | IEA | molecular_function |
| GO:0014069 | Postsynaptic density | IEA ISS | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0021535 | Cell migration in hindbrain | IEA ISS | biological_process |
| GO:0021549 | Cerebellum development | IEA | biological_process |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0030672 | Synaptic vesicle membrane | IEA ISS | cellular_component |
| GO:0032874 | Positive regulation of stress-activated MAPK cascade | IDA | biological_process |
| GO:0042692 | Muscle cell differentiation | IDA IEA | biological_process |
| GO:0045211 | Postsynaptic membrane | IEA | cellular_component |
| GO:0071526 | Semaphorin-plexin signaling pathway | IEA ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3643668744 | 0.1067527108 | 0.9999902473 | 0.6252718736 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1209538457 |
| GSE13712_SHEAR | Down | -1.1260857575 |
| GSE13712_STATIC | Down | -0.9059514624 |
| GSE19018 | Down | -0.3620762782 |
| GSE19899_A1 | Up | 0.1126503127 |
| GSE19899_A2 | Up | 0.4137230250 |
| PubMed_21979375_A1 | Down | -0.0368373875 |
| PubMed_21979375_A2 | Up | 0.3176759120 |
| GSE35957 | Down | -0.2485627985 |
| GSE36640 | Down | -0.6342056800 |
| GSE54402 | Up | 0.2402743142 |
| GSE9593 | Down | -0.3192672497 |
| GSE43922 | Up | 0.5109640170 |
| GSE24585 | Down | -0.0184818767 |
| GSE37065 | Up | 0.1584854887 |
| GSE28863_A1 | Up | 0.3398499865 |
| GSE28863_A2 | Up | 0.2725792881 |
| GSE28863_A3 | Up | 0.0032688456 |
| GSE28863_A4 | Down | -0.4415506646 |
| GSE48662 | Up | 0.1909486960 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031208 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041553 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051307 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
