HCSGD entry for PPP1R2
1. General information
| Official gene symbol | PPP1R2 |
|---|---|
| Entrez ID | 5504 |
| Gene full name | protein phosphatase 1, regulatory (inhibitor) subunit 2 |
| Other gene symbols | IPP-2 IPP2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004864 | Protein phosphatase inhibitor activity | IEA | molecular_function |
| GO:0004865 | Protein serine/threonine phosphatase inhibitor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005977 | Glycogen metabolic process | IEA | biological_process |
| GO:0006091 | Generation of precursor metabolites and energy | TAS | biological_process |
| GO:0009966 | Regulation of signal transduction | IEA | biological_process |
| GO:0043086 | Negative regulation of catalytic activity | TAS | biological_process |
| GO:0043666 | Regulation of phosphoprotein phosphatase activity | IEA | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1993697048 | 0.9643109760 | 0.8619595926 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0150279516 |
| GSE13712_SHEAR | Down | -0.1406838276 |
| GSE13712_STATIC | Up | 0.0886692223 |
| GSE19018 | Up | 0.2644958052 |
| GSE19899_A1 | Up | 0.2615047438 |
| GSE19899_A2 | Up | 0.3067670403 |
| PubMed_21979375_A1 | Up | 0.4297052229 |
| PubMed_21979375_A2 | Up | 0.1682292205 |
| GSE35957 | Up | 0.0419021604 |
| GSE36640 | Up | 0.3017916187 |
| GSE54402 | Up | 0.0699048787 |
| GSE9593 | Up | 0.0106542107 |
| GSE43922 | Up | 0.0388168216 |
| GSE24585 | Down | -0.0077185152 |
| GSE37065 | Up | 0.0619041852 |
| GSE28863_A1 | Up | 0.3372496120 |
| GSE28863_A2 | Up | 0.0468071858 |
| GSE28863_A3 | Down | -0.0310653967 |
| GSE28863_A4 | Down | -0.0028347753 |
| GSE48662 | Down | -0.2040946956 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019980 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051667 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 12489797 | Blocking phosphoprotein phosphatase activity further augments the cellular content of I and L receptors in the Alzheimer's skin fibroblast cell line |
Entries Per Page
Displaying Page of
