HCSGD entry for RNF31


1. General information

Official gene symbolRNF31
Entrez ID55072
Gene full namering finger protein 31
Other gene symbolsHOIP ZIBRA
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000209Protein polyubiquitinationIDAbiological_process
GO:0004842Ubiquitin-protein ligase activityIDA IEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005622IntracellularIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0009898Cytoplasmic side of plasma membraneISScellular_component
GO:0023035CD40 signaling pathwayISSbiological_process
GO:0035631CD40 receptor complexISScellular_component
GO:0043123Positive regulation of I-kappaB kinase/NF-kappaB signalingIDAbiological_process
GO:0043130Ubiquitin bindingIDAmolecular_function
GO:0050852T cell receptor signaling pathwayIDAbiological_process
GO:0051092Positive regulation of NF-kappaB transcription factor activityIDAbiological_process
GO:0071797LUBAC complexIDA IEAcellular_component
GO:0097039Protein linear polyubiquitinationIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.23310044450.95970093460.91676913651.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0126996903
GSE13712_SHEARUp0.1279123124
GSE13712_STATICUp0.0300048448
GSE19018Up0.1160004674
GSE19899_A1Up0.1270949230
GSE19899_A2Down-0.0181547833
PubMed_21979375_A1Down-0.0624937926
PubMed_21979375_A2Down-0.1400448088
GSE35957Up0.2204027389
GSE36640Up0.1724648233
GSE54402Up0.1708448379
GSE9593Up0.0663182441
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Up0.3208765138
GSE28863_A2Up0.5606956871
GSE28863_A3Down-0.2713223520
GSE28863_A4Down-0.0254856069
GSE48662Up0.2406843749

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.