HCSGD entry for PPP1R8
1. General information
| Official gene symbol | PPP1R8 |
|---|---|
| Entrez ID | 5511 |
| Gene full name | protein phosphatase 1, regulatory subunit 8 |
| Other gene symbols | ARD-1 ARD1 NIPP-1 NIPP1 PRO2047 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0004519 | Endonuclease activity | IEA | molecular_function |
| GO:0004865 | Protein serine/threonine phosphatase inhibitor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005681 | Spliceosomal complex | IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006355 | Regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0006397 | MRNA processing | IEA | biological_process |
| GO:0006401 | RNA catabolic process | TAS | biological_process |
| GO:0008283 | Cell proliferation | IEA | biological_process |
| GO:0008380 | RNA splicing | IEA | biological_process |
| GO:0008599 | Protein phosphatase type 1 regulator activity | IEA | molecular_function |
| GO:0008995 | Ribonuclease E activity | TAS | molecular_function |
| GO:0016607 | Nuclear speck | IDA | cellular_component |
| GO:0043086 | Negative regulation of catalytic activity | TAS | biological_process |
| GO:0050790 | Regulation of catalytic activity | TAS | biological_process |
| GO:0090305 | Nucleic acid phosphodiester bond hydrolysis | TAS | biological_process |
| GO:0090501 | RNA phosphodiester bond hydrolysis | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4394611603 | 0.5916309145 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4894385444 |
| GSE13712_SHEAR | Down | -0.2099710081 |
| GSE13712_STATIC | Down | -0.1083804265 |
| GSE19018 | Down | -0.5827556899 |
| GSE19899_A1 | Down | -0.0307291761 |
| GSE19899_A2 | Down | -0.0084772420 |
| PubMed_21979375_A1 | Up | 0.5090809657 |
| PubMed_21979375_A2 | Up | 0.2214716269 |
| GSE35957 | Down | -0.0106940896 |
| GSE36640 | Down | -0.3813880810 |
| GSE54402 | Up | 0.2031180061 |
| GSE9593 | Down | -0.0281675925 |
| GSE43922 | Up | 0.1858847750 |
| GSE24585 | Down | -0.0417523540 |
| GSE37065 | Down | -0.0217946619 |
| GSE28863_A1 | Down | -0.1756550674 |
| GSE28863_A2 | Up | 0.0410000779 |
| GSE28863_A3 | Down | -0.0771168429 |
| GSE28863_A4 | Up | 0.0913336686 |
| GSE48662 | Up | 0.2545890864 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-874-3p | MIMAT0004911 | MIRT037764 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-505-5p | MIMAT0004776 | MIRT037974 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
