HCSGD entry for PPP6R3
1. General information
| Official gene symbol | PPP6R3 |
|---|---|
| Entrez ID | 55291 |
| Gene full name | protein phosphatase 6, regulatory subunit 3 |
| Other gene symbols | C11orf23 PP6R3 SAP190 SAPL SAPLa SAPS3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0019903 | Protein phosphatase binding | IPI | molecular_function |
| GO:0043666 | Regulation of phosphoprotein phosphatase activity | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6700086433 | 0.3646418221 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3319497450 |
| GSE13712_SHEAR | Up | 0.2227405410 |
| GSE13712_STATIC | Up | 0.0298780393 |
| GSE19018 | Up | 0.1048417330 |
| GSE19899_A1 | Up | 0.1231275305 |
| GSE19899_A2 | Down | -0.2239011605 |
| PubMed_21979375_A1 | Up | 0.3250836878 |
| PubMed_21979375_A2 | Down | -0.1883814705 |
| GSE35957 | Down | -0.1155017329 |
| GSE36640 | Down | -0.2621288173 |
| GSE54402 | Up | 0.0243095444 |
| GSE9593 | Down | -0.3957346625 |
| GSE43922 | Down | -0.0407867080 |
| GSE24585 | Up | 0.2639331717 |
| GSE37065 | Up | 0.0810640073 |
| GSE28863_A1 | Up | 0.1386786929 |
| GSE28863_A2 | Up | 0.2104527999 |
| GSE28863_A3 | Down | -0.4152398174 |
| GSE28863_A4 | Up | 0.1312744846 |
| GSE48662 | Down | -0.0146684294 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020210 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025442 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027092 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039921 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050512 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
