HCSGD entry for LIN7C
1. General information
| Official gene symbol | LIN7C |
|---|---|
| Entrez ID | 55327 |
| Gene full name | lin-7 homolog C (C. elegans) |
| Other gene symbols | LIN-7-C LIN-7C MALS-3 MALS3 VELI3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005923 | Tight junction | IEA | cellular_component |
| GO:0006887 | Exocytosis | IEA | biological_process |
| GO:0007269 | Neurotransmitter secretion | IEA | biological_process |
| GO:0008092 | Cytoskeletal protein binding | IPI | molecular_function |
| GO:0014069 | Postsynaptic density | IEA | cellular_component |
| GO:0015031 | Protein transport | IEA | biological_process |
| GO:0016323 | Basolateral plasma membrane | IEA | cellular_component |
| GO:0019904 | Protein domain specific binding | IPI | molecular_function |
| GO:0030165 | PDZ domain binding | IEA | molecular_function |
| GO:0043005 | Neuron projection | IEA | cellular_component |
| GO:0045211 | Postsynaptic membrane | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6154134721 | 0.1383844307 | 0.9999902473 | 0.7162437869 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0043514033 |
| GSE13712_SHEAR | Down | -0.0225659614 |
| GSE13712_STATIC | Up | 0.1321358155 |
| GSE19018 | Down | -0.3881364948 |
| GSE19899_A1 | Up | 0.1448579047 |
| GSE19899_A2 | Down | -0.0971665286 |
| PubMed_21979375_A1 | Up | 0.8595156003 |
| PubMed_21979375_A2 | Up | 0.1537251560 |
| GSE35957 | Up | 0.2279877534 |
| GSE36640 | Down | -0.1075818694 |
| GSE54402 | Up | 0.2219297257 |
| GSE9593 | Down | -0.1681957481 |
| GSE43922 | Down | -0.1575204935 |
| GSE24585 | Down | -0.1338589649 |
| GSE37065 | Up | 0.1165373752 |
| GSE28863_A1 | Down | -0.7161697581 |
| GSE28863_A2 | Down | -0.4658831073 |
| GSE28863_A3 | Down | -0.5202549894 |
| GSE28863_A4 | Up | 0.1229511555 |
| GSE48662 | - | - |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT002793 | Microarray//Microarray;Other | Functional MTI (Weak) | 15685193 |
| hsa-miR-1 | MIMAT0000416 | MIRT002793 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-421 | MIMAT0003339 | MIRT016113 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020569 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020569 | Reporter assay;Other | Non-Functional MTI | 20584899 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022176 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-101-3p | MIMAT0000099 | MIRT027264 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-32-5p | MIMAT0000090 | MIRT028254 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-22-3p | MIMAT0000077 | MIRT030649 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030675 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031406 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | NA | hsa-miR-1 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
