HCSGD entry for H2AFY2
1. General information
| Official gene symbol | H2AFY2 |
|---|---|
| Entrez ID | 55506 |
| Gene full name | H2A histone family, member Y2 |
| Other gene symbols | macroH2A2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000786 | Nucleosome | IEA | cellular_component |
| GO:0001740 | Barr body | IDA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0006334 | Nucleosome assembly | IEA | biological_process |
| GO:0007549 | Dosage compensation | IDA | biological_process |
| GO:0016568 | Chromatin modification | IEA | biological_process |
| GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9980671745 | 0.0007558907 | 0.9999902473 | 0.0516774026 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0816864448 |
| GSE13712_SHEAR | Down | -0.2393531678 |
| GSE13712_STATIC | Down | -0.0199250909 |
| GSE19018 | Down | -0.5383103629 |
| GSE19899_A1 | Down | -0.6355536367 |
| GSE19899_A2 | Down | -0.8873551055 |
| PubMed_21979375_A1 | Down | -2.7363331280 |
| PubMed_21979375_A2 | Down | -1.7977641376 |
| GSE35957 | Down | -0.0021316432 |
| GSE36640 | Down | -2.8215550489 |
| GSE54402 | Down | -0.3100836187 |
| GSE9593 | Down | -0.5965558100 |
| GSE43922 | Down | -0.9938800327 |
| GSE24585 | Down | -0.1460102718 |
| GSE37065 | Down | -0.0453059222 |
| GSE28863_A1 | Down | -0.3602146452 |
| GSE28863_A2 | Down | -0.7911879018 |
| GSE28863_A3 | Down | -0.3028627211 |
| GSE28863_A4 | Up | 0.0295921011 |
| GSE48662 | Down | -0.1670463005 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-769-5p | MIMAT0003886 | MIRT039151 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 19648962 | 1 and macroH2A2 predicts lung cancer recurrence, identifying these histone variants as a novel tool for an improved risk stratification of cancer patients |
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