HCSGD entry for NLRP2
1. General information
| Official gene symbol | NLRP2 |
|---|---|
| Entrez ID | 55655 |
| Gene full name | NLR family, pyrin domain containing 2 |
| Other gene symbols | CLR19.9 NALP2 NBS1 PAN1 PYPAF2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0032090 | Pyrin domain binding | IPI | molecular_function |
| GO:0043280 | Positive regulation of cysteine-type endopeptidase activity involved in apoptotic process | IDA | biological_process |
| GO:0050718 | Positive regulation of interleukin-1 beta secretion | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8291302458 | 0.4182814597 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0209122287 |
| GSE13712_SHEAR | Down | -0.4766869460 |
| GSE13712_STATIC | Down | -0.7060922667 |
| GSE19018 | Up | 0.1653510793 |
| GSE19899_A1 | Up | 0.1433519685 |
| GSE19899_A2 | Up | 0.1701083820 |
| PubMed_21979375_A1 | Up | 0.1969090315 |
| PubMed_21979375_A2 | Up | 0.0873256040 |
| GSE35957 | Down | -0.0580838577 |
| GSE36640 | Up | 0.0055518712 |
| GSE54402 | Down | -0.0174349445 |
| GSE9593 | Up | 0.0681142655 |
| GSE43922 | Up | 0.0178959048 |
| GSE24585 | Down | -0.0764523837 |
| GSE37065 | Down | -0.0853718565 |
| GSE28863_A1 | Down | -0.0989760227 |
| GSE28863_A2 | Down | -0.1455813349 |
| GSE28863_A3 | Up | 0.1406248469 |
| GSE28863_A4 | Up | 0.0672199879 |
| GSE48662 | Down | -0.1933400432 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018918 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
