HCSGD entry for WDR12
1. General information
| Official gene symbol | WDR12 |
|---|---|
| Entrez ID | 55759 |
| Gene full name | WD repeat domain 12 |
| Other gene symbols | YTM1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000463 | Maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | IMP | biological_process |
| GO:0000466 | Maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) | IMP | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0007219 | Notch signaling pathway | IEA | biological_process |
| GO:0008283 | Cell proliferation | IMP | biological_process |
| GO:0030687 | Preribosome, large subunit precursor | IDA | cellular_component |
| GO:0042273 | Ribosomal large subunit biogenesis | IC | biological_process |
| GO:0043021 | Ribonucleoprotein complex binding | IEA | molecular_function |
| GO:0070545 | PeBoW complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1696019984 | 0.4385372668 | 0.8110636265 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2827023470 |
| GSE13712_SHEAR | Up | 0.1679691328 |
| GSE13712_STATIC | Up | 0.2221117845 |
| GSE19018 | Down | -0.3276916831 |
| GSE19899_A1 | Up | 0.2310708665 |
| GSE19899_A2 | Up | 0.4996084584 |
| PubMed_21979375_A1 | Up | 0.7410364272 |
| PubMed_21979375_A2 | Up | 0.3542447603 |
| GSE35957 | Down | -0.3168014529 |
| GSE36640 | Down | -0.2577194358 |
| GSE54402 | Up | 0.4025890275 |
| GSE9593 | Up | 0.0585520813 |
| GSE43922 | Up | 0.1739366776 |
| GSE24585 | Down | -0.4141086517 |
| GSE37065 | Down | -0.1365093891 |
| GSE28863_A1 | Down | -0.1639997434 |
| GSE28863_A2 | Up | 0.2719559230 |
| GSE28863_A3 | Down | -0.4698138497 |
| GSE28863_A4 | Down | -0.0190540905 |
| GSE48662 | Down | -0.3869777567 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028635 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041501 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
