HCSGD entry for ADCY10
1. General information
| Official gene symbol | ADCY10 |
|---|---|
| Entrez ID | 55811 |
| Gene full name | adenylate cyclase 10 (soluble) |
| Other gene symbols | HCA2 RP1-313L4.2 SAC SACI Sacy |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | IEA | molecular_function |
| GO:0004016 | Adenylate cyclase activity | NAS | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0005829 | Cytosol | NAS | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006171 | CAMP biosynthetic process | NAS | biological_process |
| GO:0007283 | Spermatogenesis | IEA | biological_process |
| GO:0030145 | Manganese ion binding | IEA | molecular_function |
| GO:0030424 | Axon | IEA | cellular_component |
| GO:0030425 | Dendrite | IEA | cellular_component |
| GO:0030426 | Growth cone | IEA | cellular_component |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0043025 | Neuronal cell body | IEA | cellular_component |
| GO:0043065 | Positive regulation of apoptotic process | IEA | biological_process |
| GO:0045177 | Apical part of cell | IEA | cellular_component |
| GO:0045178 | Basal part of cell | IEA | cellular_component |
| GO:0048471 | Perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0051117 | ATPase binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8201674442 | 0.8255856388 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0464829600 |
| GSE13712_SHEAR | Down | -0.0628707730 |
| GSE13712_STATIC | Up | 0.0333878349 |
| GSE19018 | Up | 0.1620444303 |
| GSE19899_A1 | Down | -0.0054731109 |
| GSE19899_A2 | Down | -0.1332608499 |
| PubMed_21979375_A1 | Down | -0.1270634874 |
| PubMed_21979375_A2 | Up | 0.0276640186 |
| GSE35957 | Up | 0.0273621469 |
| GSE36640 | Up | 0.0791662014 |
| GSE54402 | Up | 0.0163214057 |
| GSE9593 | Up | 0.0475709386 |
| GSE43922 | Up | 0.0175094150 |
| GSE24585 | Up | 0.0670834803 |
| GSE37065 | Up | 0.0115321121 |
| GSE28863_A1 | Down | -0.0892264659 |
| GSE28863_A2 | Up | 0.1116458435 |
| GSE28863_A3 | Up | 0.0591816602 |
| GSE28863_A4 | Down | -0.0347222122 |
| GSE48662 | Up | 0.0203148767 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 19852768 | A dual-activation, adenoviral-based system for the controlled induction of DNA double-strand breaks by the restriction endonuclease SacI |
| 19852768 | We generated a single adenoviral vector containing a tet-inducible, composite SacI restriction endonuclease/estrogen receptor (ERT2) gene, and a constitutively expressed reverse transactivator (rtTA) gene |
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