HCSGD entry for VIMP

1. General information

Official gene symbolVIMP
Entrez ID55829
Gene full nameVCP-interacting membrane protein
Other gene symbolsADO15 SBBI8 SELS SEPS1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002865Negative regulation of acute inflammatory response to antigenic stimulusIMPbiological_process
GO:0004872Receptor activityNASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005881Cytoplasmic microtubuleIDAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006111Regulation of gluconeogenesisTASbiological_process
GO:0006886Intracellular protein transportIEAbiological_process
GO:0006983ER overload responseIDA IMPbiological_process
GO:0008430Selenium bindingIEAmolecular_function
GO:0009749Response to glucoseIEPbiological_process
GO:0016209Antioxidant activityIDAmolecular_function
GO:0019899Enzyme bindingIPImolecular_function
GO:0030176Integral component of endoplasmic reticulum membraneIDA IEAcellular_component
GO:0030433ER-associated ubiquitin-dependent protein catabolic processIDAbiological_process
GO:0030968Endoplasmic reticulum unfolded protein responseIDAbiological_process
GO:0030970Retrograde protein transport, ER to cytosolIDAbiological_process
GO:0032715Negative regulation of interleukin-6 productionISSbiological_process
GO:0032720Negative regulation of tumor necrosis factor productionISSbiological_process
GO:0032869Cellular response to insulin stimulusTASbiological_process
GO:0034361Very-low-density lipoprotein particleIDAcellular_component
GO:0034362Low-density lipoprotein particleIDAcellular_component
GO:0034599Cellular response to oxidative stressIMPbiological_process
GO:0045184Establishment of protein localizationTASbiological_process
GO:0045454Cell redox homeostasisIDAbiological_process
GO:0045719Negative regulation of glycogen biosynthetic processTASbiological_process
GO:0046325Negative regulation of glucose importTASbiological_process
GO:0050728Negative regulation of inflammatory responseICbiological_process
GO:0051771Negative regulation of nitric-oxide synthase biosynthetic processIMPbiological_process
GO:0051775Response to redox stateIDAbiological_process
GO:0071222Cellular response to lipopolysaccharideIMPbiological_process
GO:0080164Regulation of nitric oxide metabolic processIMPbiological_process
GO:1902236Negative regulation of intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stressIMPbiological_process
GO:2000110Negative regulation of macrophage apoptotic processIMPbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.52760732870.35809670610.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0340865497
GSE13712_SHEARDown-0.0419305482
GSE13712_STATICDown-0.0458590680
GSE19018Down-0.4987601924
GSE19899_A1Down-0.2701997819
GSE19899_A2Up0.0326616626
PubMed_21979375_A1Up0.1019883718
PubMed_21979375_A2Down-0.3180683311
GSE35957Up0.1280067801
GSE36640Up0.4162315892
GSE54402Up0.1468704667
GSE9593Up0.1774010805
GSE43922Up0.0937913767
GSE24585Up0.0321231768
GSE37065Up0.0068888453
GSE28863_A1Up0.2373826244
GSE28863_A2Up0.4580411706
GSE28863_A3Down-0.3680794417
GSE28863_A4Up0.0863626286
GSE48662Down-0.4343412008

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

23634235Amongst the genes were IRAK3, SelS, HSPA5, HERPUD1, DNAJB9, SEPR1, C18orf55, ARF4, RINT1, NXT1, CADPS2, COG6, and GLRX5
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