HCSGD entry for ECHDC1
1. General information
| Official gene symbol | ECHDC1 |
|---|---|
| Entrez ID | 55862 |
| Gene full name | enoyl CoA hydratase domain containing 1 |
| Other gene symbols | MMCD dJ351K20.2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0004492 | Methylmalonyl-CoA decarboxylase activity | IEA | molecular_function |
| GO:0005829 | Cytosol | IEA ISS | cellular_component |
| GO:0016831 | Carboxy-lyase activity | IEA ISS | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9368177843 | 0.0362331256 | 0.9999902473 | 0.3584160090 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6002488516 |
| GSE13712_SHEAR | Down | -0.3253319633 |
| GSE13712_STATIC | Down | -0.1253894057 |
| GSE19018 | Down | -0.3981300591 |
| GSE19899_A1 | Down | -0.3228968888 |
| GSE19899_A2 | Down | -0.3827880647 |
| PubMed_21979375_A1 | Down | -0.5795952959 |
| PubMed_21979375_A2 | Down | -0.4733696680 |
| GSE35957 | Up | 0.0903218765 |
| GSE36640 | Down | -0.3446354757 |
| GSE54402 | Up | 0.2756528095 |
| GSE9593 | Down | -0.2287371924 |
| GSE43922 | Down | -0.4181699551 |
| GSE24585 | Down | -0.5767144105 |
| GSE37065 | Down | -0.1162331718 |
| GSE28863_A1 | Up | 0.0346602293 |
| GSE28863_A2 | Up | 0.2721343963 |
| GSE28863_A3 | Down | -0.0503635363 |
| GSE28863_A4 | Down | -0.0166694369 |
| GSE48662 | Down | -0.2640686809 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT000834 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-15a-5p | MIMAT0000068 | MIRT000835 | Microarray | Functional MTI (Weak) | 18362358 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048213 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-15a-5p | MIMAT0000068 | NA | hsa-miR-15a | 18362358 | |||
| hsa-miR-16-5p | MIMAT0000069 | NA | hsa-miR-16 | 18362358 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
