HCSGD entry for ASH1L


1. General information

Official gene symbolASH1L
Entrez ID55870
Gene full nameash1 (absent, small, or homeotic)-like (Drosophila)
Other gene symbolsASH1 ASH1L1 KMT2H
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005694ChromosomeIEAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005794Golgi apparatusIDAcellular_component
GO:0005923Tight junctionIEAcellular_component
GO:0006323DNA packagingTASbiological_process
GO:0006355Regulation of transcription, DNA-templatedIEAbiological_process
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0018024Histone-lysine N-methyltransferase activityIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03863105510.75908307820.44421494101.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0068029570
GSE13712_SHEARUp0.1927100807
GSE13712_STATICUp0.0859412047
GSE19018Up0.1313369870
GSE19899_A1Up0.1696096127
GSE19899_A2Up0.0722784569
PubMed_21979375_A1Down-0.3898250853
PubMed_21979375_A2Down-0.2119498788
GSE35957Up0.0951337934
GSE36640Up0.1039992502
GSE54402Up0.0956250159
GSE9593Up0.1588677003
GSE43922Down-0.0310017361
GSE24585Up0.3274123955
GSE37065Up0.1007138452
GSE28863_A1Up1.3444049688
GSE28863_A2Up1.6372006855
GSE28863_A3Down-0.2081241308
GSE28863_A4Down-0.4961363241
GSE48662Up0.5508921131

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-103a-3pMIMAT0000101MIRT027138SequencingFunctional MTI (Weak)20371350
hsa-miR-16-5pMIMAT0000069MIRT031796SequencingFunctional MTI (Weak)20371350
hsa-miR-877-3pMIMAT0004950MIRT037090CLASHFunctional MTI (Weak)23622248
hsa-miR-625-5pMIMAT0003294MIRT039596CLASHFunctional MTI (Weak)23622248
hsa-miR-193b-3pMIMAT0002819MIRT041462CLASHFunctional MTI (Weak)23622248
hsa-miR-361-5pMIMAT0000703MIRT044085CLASHFunctional MTI (Weak)23622248
hsa-miR-185-5pMIMAT0000455MIRT045370CLASHFunctional MTI (Weak)23622248
hsa-miR-17-5pMIMAT0000070MIRT050880CLASHFunctional MTI (Weak)23622248
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.