HCSGD entry for PBK
1. General information
| Official gene symbol | PBK |
|---|---|
| Entrez ID | 55872 |
| Gene full name | PDZ binding kinase |
| Other gene symbols | CT84 Nori-3 SPK TOPK |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004674 | Protein serine/threonine kinase activity | IEA TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005575 | Cellular_component | ND | cellular_component |
| GO:0007067 | Mitosis | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5413517951 | 0.0000059800 | 0.9999902473 | 0.0069833333 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -2.2239638022 |
| GSE13712_SHEAR | Down | -0.7219942052 |
| GSE13712_STATIC | Down | -0.9752532380 |
| GSE19018 | Up | 0.1437569188 |
| GSE19899_A1 | Down | -3.7236908365 |
| GSE19899_A2 | Down | -5.2688382022 |
| PubMed_21979375_A1 | Down | -5.7924737317 |
| PubMed_21979375_A2 | Down | -7.3224833094 |
| GSE35957 | Down | -5.9450902538 |
| GSE36640 | Down | -5.5469274166 |
| GSE54402 | Down | -1.6058971041 |
| GSE9593 | Down | -2.4229130124 |
| GSE43922 | Down | -3.6551674927 |
| GSE24585 | Down | -0.0014356011 |
| GSE37065 | Down | -1.0933596191 |
| GSE28863_A1 | Down | -0.2869483333 |
| GSE28863_A2 | Up | 2.1949359323 |
| GSE28863_A3 | Down | -0.5884885797 |
| GSE28863_A4 | Up | 0.6448024788 |
| GSE48662 | Down | -2.8853284251 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | MIRT004449 | Microarray | Functional MTI (Weak) | 15685193 |
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- mirRecord
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-373-3p | MIMAT0000726 | NA | hsa-miR-373 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
