HCSGD entry for MESP1

1. General information

Official gene symbolMESP1
Entrez ID55897
Gene full namemesoderm posterior 1 homolog (mouse)
Other gene symbolsbHLHc5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001947Heart loopingISSbiological_process
GO:0003139Secondary heart field specificationISSbiological_process
GO:0003143Embryonic heart tube morphogenesisISSbiological_process
GO:0003210Cardiac atrium formationIMPbiological_process
GO:0003211Cardiac ventricle formationIMPbiological_process
GO:0003236Sinus venosus morphogenesisISSbiological_process
GO:0003241Growth involved in heart morphogenesisISSbiological_process
GO:0003259Cardioblast anterior-lateral migrationISSbiological_process
GO:0003700Sequence-specific DNA binding transcription factor activityIDAmolecular_function
GO:0005634NucleusICcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0007219Notch signaling pathwayIEAbiological_process
GO:0007369GastrulationISSbiological_process
GO:0008078Mesodermal cell migrationIEAbiological_process
GO:0022008NeurogenesisIMPbiological_process
GO:0023019Signal transduction involved in regulation of gene expressionIEAbiological_process
GO:0035326Enhancer bindingIEAmolecular_function
GO:0035481Positive regulation of Notch signaling pathway involved in heart inductionIEAbiological_process
GO:0042662Negative regulation of mesodermal cell fate specificationISSbiological_process
GO:0042664Negative regulation of endodermal cell fate specificationISSbiological_process
GO:0044212Transcription regulatory region DNA bindingIDAmolecular_function
GO:0045446Endothelial cell differentiationIMPbiological_process
GO:0045747Positive regulation of Notch signaling pathwayISSbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedISSbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedISSbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDA ISSbiological_process
GO:0046983Protein dimerization activityIEAmolecular_function
GO:0048368Lateral mesoderm developmentISSbiological_process
GO:0051155Positive regulation of striated muscle cell differentiationISSbiological_process
GO:0055007Cardiac muscle cell differentiationIMPbiological_process
GO:0060913Cardiac cell fate determinationISSbiological_process
GO:0060921Sinoatrial node cell differentiationIMPbiological_process
GO:0060947Cardiac vascular smooth muscle cell differentiationIMPbiological_process
GO:0060975Cardioblast migration to the midline involved in heart field formationISSbiological_process
GO:0070368Positive regulation of hepatocyte differentiationISSbiological_process
GO:0090082Positive regulation of heart induction by negative regulation of canonical Wnt signaling pathwayISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.40638707120.85988183580.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.1021515715
GSE13712_SHEARDown-0.2857281413
GSE13712_STATICDown-0.1483727797
GSE19018Up0.0916939353
GSE19899_A1Up0.0150426286
GSE19899_A2Up0.2261103627
PubMed_21979375_A1Down-0.0276430846
PubMed_21979375_A2Up0.0286566857
GSE35957Up0.0906548844
GSE36640Down-0.0290926808
GSE54402Up0.0632446110
GSE9593Down-0.1485440537
GSE43922Up0.1523254196
GSE24585Down-0.0230487728
GSE37065Down-0.0862006174
GSE28863_A1Down-0.0295235332
GSE28863_A2Up0.0628721934
GSE28863_A3Up0.5442592459
GSE28863_A4Up0.2271099178
GSE48662Up0.2752619615

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.