HCSGD entry for DMAP1
1. General information
| Official gene symbol | DMAP1 |
|---|---|
| Entrez ID | 55929 |
| Gene full name | DNA methyltransferase 1 associated protein 1 |
| Other gene symbols | DNMAP1 DNMTAP1 EAF2 MEAF2 SWC4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IDA | biological_process |
| GO:0001103 | RNA polymerase II repressing transcription factor binding | IDA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0003714 | Transcription corepressor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA NAS | cellular_component |
| GO:0005657 | Replication fork | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0006306 | DNA methylation | TAS | biological_process |
| GO:0006338 | Chromatin remodeling | IEA | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0035267 | NuA4 histone acetyltransferase complex | IDA IEA | cellular_component |
| GO:0040008 | Regulation of growth | IEA | biological_process |
| GO:0042993 | Positive regulation of transcription factor import into nucleus | IDA | biological_process |
| GO:0043967 | Histone H4 acetylation | IDA IEA | biological_process |
| GO:0043968 | Histone H2A acetylation | IDA IEA | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IEA NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8213963831 | 0.2523590859 | 0.9999902473 | 0.9643985192 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0373587941 |
| GSE13712_SHEAR | Down | -0.2457120049 |
| GSE13712_STATIC | Down | -0.0451050535 |
| GSE19018 | Up | 0.0194351388 |
| GSE19899_A1 | Down | -0.4356729464 |
| GSE19899_A2 | Down | -0.2142141247 |
| PubMed_21979375_A1 | Up | 0.7507672394 |
| PubMed_21979375_A2 | Down | -0.3524007036 |
| GSE35957 | Down | -0.3706242845 |
| GSE36640 | Up | 0.1074961828 |
| GSE54402 | Up | 0.0365434059 |
| GSE9593 | Down | -0.2120338715 |
| GSE43922 | Up | 0.0419381124 |
| GSE24585 | Up | 0.1898039234 |
| GSE37065 | Down | -0.0633923583 |
| GSE28863_A1 | Down | -0.0080638416 |
| GSE28863_A2 | Up | 0.0257352744 |
| GSE28863_A3 | Down | -0.3915584445 |
| GSE28863_A4 | Down | -0.1289425830 |
| GSE48662 | Up | 0.2032352792 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT031691 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043441 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
